The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel.
about
Novel role of ouabain as a cystogenic factor in autosomal dominant polycystic kidney diseaseRegulation of calcium signaling by polycystin-2A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney diseasePolycystin-1 interacts with intermediate filaments.Odors activate dual pathways, a TRPC2 and a AA-dependent pathway, in mouse vomeronasal neurons.The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit.Cyclic AMP-mediated cyst expansionTolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressinNon-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP.STAM and Hrs down-regulate ciliary TRP receptorsRegulation of AE2-mediated Cl- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domainCalmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells.Novel insights into TRPV4 function in the kidney.Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.Phosphodiesterase Isoform Regulation of Cell Proliferation and Fluid Secretion in Autosomal Dominant Polycystic Kidney Disease.Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression.Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease.Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling.Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells.A novel dephosphorylation-activated conductance in a mouse renal collecting duct cell line.More than colocalizing with polycystin-1, polycystin-L is in the centrosome.Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: mutational and functional analysis.Amino acid transporter CAATCH1 is also an amino acid-gated cation channel.Structure-function relationships of AE2 regulation by Ca(i)(2+)-sensitive stimulators NH(4+) and hypertonicity.Apparent receptor-mediated activation of Ca2+-dependent conductive Cl- transport by shark-derived polyaminosterols.Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.The N-terminal extracellular domain is required for polycystin-1-dependent channel activity.Regulation of AE2 anion exchanger by intracellular pH: critical regions of the NH(2)-terminal cytoplasmic domain.Gαi-mediated TRPC4 activation by polycystin-1 contributes to endothelial function via STAT1 activation.
P2860
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P2860
The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@ast
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@en
type
label
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@ast
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@en
prefLabel
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@ast
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@en
P2093
P2860
P356
P1476
The cytoplasmic C-terminal fra ...... Ca2+-permeable cation channel.
@en
P2093
Chernova MN
Stuart-Tilley AK
Vandorpe DH
P2860
P304
P356
10.1074/JBC.M006252200
P407
P577
2000-10-23T00:00:00Z