Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids.
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Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacyHAb18G/CD147 cell-cell contacts confer resistance of a HEK293 subpopulation to anoikis in an E-cadherin-dependent mannerMicroenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes.Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death.Improved Methods to Generate Spheroid Cultures from Tumor Cells, Tumor Cells & Fibroblasts or Tumor-Fragments: Microenvironment, Microvesicles and MiRNA.The use of 3-D cultures for high-throughput screening: the multicellular spheroid model.A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.Low-dose radiation hyper-radiosensitivity in multicellular tumour spheroidsThe tumor microenvironment is a dominant force in multidrug resistance.Radiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium.E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase.Tumor-derived spheroids: Relevance to cancer stem cells and clinical applicationsBehavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation.Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.Slow down to stay alive: HER4 protects against cellular stress and confers chemoresistance in neuroblastomaNew-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells.Tissue dynamics spectroscopy for three-dimensional tissue-based drug screening.Inherent aggressive character of invasive and non-invasive cells dictates the in vitro migration pattern of multicellular spheroid.Protein and phosphoprotein levels in glioma and adenocarcinoma cell lines grown in normoxia and hypoxia in monolayer and three-dimensional cultures.Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach.Survival in three dimensionsATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: What is the way forward?
P2860
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P2860
Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@ast
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@en
type
label
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@ast
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@en
prefLabel
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@ast
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@en
P1476
Resistance of tumor cells to c ...... of solid tumors and spheroids.
@en
P2093
P304
P356
10.1016/S0091-679X(01)64015-9
P577
2001-01-01T00:00:00Z