Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
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Gene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotypeImputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Interferon regulatory factor 6 regulates keratinocyte migration.Periderm prevents pathological epithelial adhesions during embryogenesis.Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis.Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22.Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.Clinical and molecular findings in a Moroccan patient with popliteal pterygium syndrome: a case reportA composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms.IRF6 Is Involved in the Regulation of Cell Proliferation and Transformation in MCF10A Cells Downstream of Notch SignalingExpression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor.S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma.IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion.The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis.Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development.MiR-320e is a novel prognostic biomarker in colorectal cancer.Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis.p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palateToward an orofacial gene regulatory network.Cutaneous clear cell/signet-ring cell squamous cell carcinoma arising in the right thigh of a patient with type 2 diabetes: combined morphologic, immunohistochemical, and etiologic analysis.Comparative analysis of IRF6 variants in families with Van der Woude syndrome and popliteal pterygium syndrome using public whole-exome databasesMouse Genetic Models Reveal Surprising Functions of IkB Kinase Alpha in Skin Development and Skin Carcinogenesis.Chromatin Landscape of the IRF Genes and Role of the Epigenetic Reader BRD4.Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm developmentA multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.Crosstalk among p53 family members in cutaneous carcinoma.Grainyhead-like Transcription Factors in Craniofacial Development.Interferon Regulatory Factor 6 Promotes Keratinocyte Differentiation in Response to Porphyromonas gingivalis.IRF6 expression in basal epithelium partially rescues Irf6 knockout mice.Knockdown of IRF6 Attenuates Hydrogen Dioxide-Induced Oxidative Stress via Inhibiting Mitochondrial Dysfunction in HT22 Cells.TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes.Reviewing the genetic alterations in high-risk cutaneous squamous cell carcinoma: A search for prognostic markers and therapeutic targets.Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development.Genetic analysis of IRF6, a gene involved in craniofacial midline formation, in relation to pituitary and facial morphology of patients with idiopathic growth hormone deficiency.Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63.Association of TFAP2A gene polymorphism with susceptibility to non-syndromic cleft lip with or without palate risk in south Indian population.
P2860
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P2860
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@ast
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@en
type
label
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@ast
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@en
prefLabel
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@ast
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@en
P2093
P2860
P50
P356
P1476
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.
@en
P2093
Barbara Marinari
Elisabetta Botti
Francesca De Nicola
Francesca Moretti
Giovanni Blandino
Giulia Spallone
Luisa Guerrini
Maurizio Fanciulli
Paolo D'Onorio De Meo
Sergio Chimenti
P2860
P304
13710-13715
P356
10.1073/PNAS.1110931108
P407
P577
2011-08-01T00:00:00Z