Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation. - Wikidata - wikimedia - TriplyDB

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation.

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation.

http://www.wikidata.org/entity/Q31836174

about

Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19 Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication Renal medullary ETB receptors produce diuresis and natriuresis via NOS1 Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha)Sub-Nanomolar Sensitivity of Nitric Oxide Mediated Regulation of cGMP and Vasomotor Reactivity in Vascular Smooth Muscle.Screening for the optimal specificity profile of protein kinase C using electrospray mass-spectrometry.Peptide arrays for kinase profiling.cGMP-dependent protein kinase I interacts with TRIM39R, a novel Rpp21 domain-containing TRIM protein.(D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha.Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition Design of a bioactive cell-penetrating peptide: when a transduction domain does more than transduce cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Potent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins.cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation.sGC{alpha}1 mediates the negative inotropic effects of NO in cardiac myocytes independent of changes in calcium handling Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors.Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer.Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway.Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα Platelet-derived HMGB1 is a critical mediator of thrombosis.Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes A cyclic GMP-dependent calcium-activated chloride current in smooth-muscle cells from rat mesenteric resistance arteries Melatonin inhibits nitric oxide signaling by increasing PDE5 phosphorylation in coronary arteries.The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells.Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG Cellulose-bound peptide arrays: preparation and applications.Effects of Acetaminophen on Left Atrial Contractility.Mode of action of cGMP-dependent protein kinase-specific inhibitors probed by photoaffinity cross-linking mass spectrometry.cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.Deciphering enzyme function using peptide arrays.cGMP-Dependent Protein Kinase Inhibitors in Health and Disease.Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool.Anti-tumor properties of the cGMP/protein kinase G inhibitor DT3 in pancreatic adenocarcinoma.Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility.Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.

P2860

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P2860

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation.

http://www.wikidata.org/entity/Q31836174

description

2000 nî lūn-bûn

@nan

2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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type

label

Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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prefLabel

Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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PNAS.97.26.14772

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Proceedings of the National Academy of Sciences of the United States of America

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Highly specific, membrane-perm ...... NO-induced cerebral dilation.

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P2093

C K Nickl

http://www.w3.org/2001/XMLSchema#string

J E Brayden

http://www.w3.org/2001/XMLSchema#string

M S Taylor

http://www.w3.org/2001/XMLSchema#string

R Frank

http://www.w3.org/2001/XMLSchema#string

W J Tegge

http://www.w3.org/2001/XMLSchema#string

W R Dostmann

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha

Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta

cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

Delineation of selective cyclic GMP-dependent protein kinase Ialpha substrate and inhibitor peptides based on combinatorial peptide libraries on paper.

Analysis of protein kinase substrate specificity by the use of peptide libraries on cellulose paper (SPOT-method).

Tat-mediated delivery of heterologous proteins into cells.

Determination of cyclic nucleotide-dependent protein kinase substrate specificity by the use of peptide libraries on cellulose paper.

cGMP signaling through cAMP- and cGMP-dependent protein kinases.

The activation of expressed cGMP-dependent protein kinase isozymes I alpha and I beta is determined by the different amino-termini.

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11121077

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18994

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