Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein.
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Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression.alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson diseasePassive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicityProducts of Cu(II)-catalyzed oxidation of alpha-synuclein fragments containing M1-D2 and H50 residues in the presence of hydrogen peroxide.Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseasesSelective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathyMutant alpha-synuclein exacerbates age-related decrease of neurogenesis.Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease.Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synucleinalpha-Synuclein: a therapeutic target for Parkinson's disease?Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus.Alpha-Synuclein Suppresses Retinoic Acid-Induced Neuronal Differentiation by Targeting the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway.Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathologyMesenchymal Stem Cells Stabilize Axonal Transports for Autophagic Clearance of α-Synuclein in Parkinsonian Models.Pathological and clinical aspects of alpha/beta synuclein in Parkinson's disease and related disorders.Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease.Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease.Enhanced lysosomal pathology caused by beta-synuclein mutants linked to dementia with Lewy bodies.Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein.alpha-Synuclein stimulates differentiation of osteosarcoma cells: relevance to down-regulation of proteasome activity.Effects of the cholesterol-lowering compound methyl-beta-cyclodextrin in models of alpha-synucleinopathy.A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition.An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model.Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons.Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology
P2860
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P2860
Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@ast
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@en
type
label
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@ast
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@en
prefLabel
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@ast
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@en
P2093
P356
P1476
Reduced neuritic outgrowth and ...... ed with human alpha-synuclein.
@en
P2093
Hashimoto M
Mackowski B
Rockenstein E
Takenouchi T
P304
P356
10.1006/MCNE.2000.0923
P577
2001-01-01T00:00:00Z