Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Item
http://www.wikidata.org/entity/Q31852295
Safety, pharmacokinetics, and antiretroviral activity of multiple doses of ibalizumab (formerly TNX-355), an anti-CD4 monoclonal antibody, in human immunodeficiency virus type 1-infected adultsIgG4 Characteristics and Functions in Cancer ImmunityAgeing Is Associated with Decreases in Appetite and Energy Intake--A Meta-Analysis in Healthy AdultsClinical trials of transplant tolerance: slow but steady progress.T cell targeted immunotherapy for autoimmune disease.The poor contribution of chimpanzee experiments to biomedical progress.Targeting CLEC9A delivers antigen to human CD141(+) DC for CD4(+) and CD8(+)T cell recognitionMonoclonal antibody-induced cytokine-release syndrome.Glycation, Oxidation and Glycoxidation of IgG: A Biophysical, Biochemical, Immunological and Hematological study.Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions.Human immunodeficiency virus type 1 escape from cyclotriazadisulfonamide-induced CD4-targeted entry inhibition is associated with increased neutralizing antibody susceptibility.Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay.Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant.
P2860

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Item
http://www.wikidata.org/entity/Q31852295
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@ast
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@en
type
label
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@ast
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@en
prefLabel
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@ast
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Modification of the Fc region ...... CD4(+) T cells in chimpanzees.
@en
P2093
P304
P31
P356
P433
P478
P577
P698
P921