Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?
about
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteinsCD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathwaysTrojan-horse nanotube on-command intracellular drug deliveryCeramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases.Enlargement and contracture of C2-ceramide channels.ELIGLUSTAT TARTRATE: Glucosylceramide Synthase Inhibitor Treatment of Type 1 Gaucher Disease.Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.The development of aggressive cancer: a possible role for sphingolipids.Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cellsIncreased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes.LC-MS Based Sphingolipidomic Study on A2780 Human Ovarian Cancer Cell Line and its Taxol-resistant Strain.Use of liposomes as drug delivery vehicles for treatment of melanoma.gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials.Allylic structures in cancer drugs and body metabolites that control cell life and death.Bioactive lipids-based pH sensitive micelles for co-delivery of doxorubicin and ceramide to overcome multidrug resistance in leukemia.Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism.Characterization of a quasicrystalline phase in codispersions of phosphatidylethanolamine and glucocerebroside.Selective induction of apoptosis in MCF7 cancer-cell by targeted liposomes functionalised with mannose-6-phosphate.Ceramide in nitric oxide inhibition of glioma cell growth. Evidence for the involvement of ceramide traffic.Stereoselective synthesis of (2S,3S,4Z)-4-fluoro-1,3-dihydroxy-2-(octadecanoylamino)octadec-4-ene, [(Z)-4-fluoroceramide], and its phase behavior at the air/water interface.Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells.Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing.Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells.Formation of glucosylceramide and sterol glucoside by a UDP-glucose-dependent glucosylceramide synthase from cotton expressed in Pichia pastoris.Highly efficient and stereoselective synthesis of beta-glycolipids.Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs.Ceramide levels are inversely associated with malignant progression of human glial tumors.
P2860
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P2860
Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@ast
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@en
type
label
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@ast
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@en
prefLabel
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@ast
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@en
P1433
P1476
Killing cancer cells by poly-d ...... ypothesis whose time has come?
@en
P2093
P304
P356
10.1046/J.1432-1033.2001.01845.X
P407
P577
2001-01-01T00:00:00Z