Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters.
about
Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductaseIsolation and characterization of a digoxin transporter and its rat homologue expressed in the kidneyEvolutionary conservation predicts function of variants of the human organic cation transporter, OCT1The role of drug transporters in the kidney: lessons from tenofovirMetformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endotheliumcis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospectsTransporters at CNS barrier sites: obstacles or opportunities for drug delivery?Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineAltered Gene Expression in the Schistosome-Transmitting Snail Biomphalaria glabrata following Exposure to Niclosamide, the Active Ingredient in the Widely Used Molluscicide BayluscideIndividualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Recent advances in pharmacokinetic extrapolation from preclinical data to humans.Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake.Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances.Novel inhibitors of human organic cation/carnitine transporter (hOCTN2) via computational modeling and in vitro testingTransport of cimetidine by flounder and human renal organic anion transporter 1.Pharmacogenetics of Anti-Diabetes Drugs.Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1Renal handling of amphotericin B and amphotericin B-deoxycholate and potential renal drug-drug interactions with selected antivirals.Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters.Alternative splicing and diversity of renal transporters.OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects.Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differencesPharmacogenomic considerations in drug delivery.Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin actionMolecular and cellular physiology of renal organic cation and anion transport.Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2.Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1).Drug-drug interactions involving membrane transporters in the human kidney.Strategies to assess the drug interaction potential in translational medicine.Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discriminationMetformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine.Effects of drug transporters on volume of distribution.Regulation of renal organic anion transporter 3 (SLC22A8) expression and function by the integrity of lipid raft domains and their associated cytoskeletonDrug transporter pharmacogenetics in nucleoside-based therapies.Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.Drug transporters in the nasal epithelium: an overview of strategies in targeted drug delivery.Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions.The effect of acyclovir on the tubular secretion of creatinine in vitro.
P2860
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P2860
Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Transporters involved in the e ...... d organic cation transporters.
@ast
Transporters involved in the e ...... d organic cation transporters.
@en
type
label
Transporters involved in the e ...... d organic cation transporters.
@ast
Transporters involved in the e ...... d organic cation transporters.
@en
prefLabel
Transporters involved in the e ...... d organic cation transporters.
@ast
Transporters involved in the e ...... d organic cation transporters.
@en
P2093
P1476
Transporters involved in the e ...... d organic cation transporters.
@en
P2093
Dresser MJ
Giacomini KM
Leabman MK
P304
P356
10.1002/1520-6017(200104)90:4<397::AID-JPS1000>3.0.CO;2-D
P407
P577
2001-04-01T00:00:00Z