Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.
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PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6Preliminary investigation of the contribution of CYP2A6, CYP2B6, and UGT1A9 polymorphisms on artesunate-mefloquine treatment response in Burmese patients with Plasmodium falciparum malaria.Biomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population.Phase II study of S-1 combined with oxaliplatin as therapy for patients with metastatic biliary tract cancer: influence of the CYP2A6 polymorphism on pharmacokinetics and clinical activity.Association of CYP2A6*4 with susceptibility of lung cancer: a meta-analysis.Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level.Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.Biomarkers of Response to Smoking Cessation Pharmacotherapies: Progress to Date.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Genetics and drug use as a complex phenotype.Pharmacogenomics in cardiovascular disease: the role of single nucleotide polymorphisms in improving drug therapy.Overview of the pharmacogenomics of cigarette smoking.CYP2A6 polymorphisms: is there a role for pharmacogenomics in preventing coumarin-induced hepatotoxicity in lymphedema patients?Genetic variability in CYP2A6 and the pharmacokinetics of nicotine.Past and future applications of CYP450-genetic polymorphisms for biomonitoring of environmental toxicants.Nicotine dependence pharmacogenetics: role of genetic variation in nicotine-metabolizing enzymesCYP2A6 polymorphisms and risk for tobacco-related cancers.A review of smoking behavior and smokers evidence (chemical modification, inducing nicotine metabolism, and individual variations by genotype: dopaminergic function and personality traits).Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.Nicotine Metabolite Ratio Is Associated With Lozenge Use But Not Quitting in Smokeless Tobacco Users.The Nicotine Metabolite Ratio in Pregnancy Measured by trans-3'-Hydroxycotinine to Cotinine Ratio: Characteristics and Relationship With Smoking Cessation.Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolismHuman blood concentrations of cotinine, a biomonitoring marker for tobacco smoke, extrapolated from nicotine metabolism in rats and humans and physiologically based pharmacokinetic modeling.Isoflavones inhibit nicotine C-oxidation catalyzed by human CYP2A6.Inter-gene correlation on oligonucleotide arrays: how much does normalization matter?Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma.Novel human CYP2A6 alleles confound gene deletion analysis.CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis.Does ethnic ancestry play a role in smoking?Differences between Spaniards and Ecuadorians in CYP2A6 allele frequencies: comparison with other populations.Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy.CYP2A6 gene polymorphism and personality traits for NEO-FFI on the smoking behavior of youths.Gene, ethnic and gender influences predisposition of adverse drug reactions to artesunate among Malaysians.Cytochrome p450 metabolism of betel quid-derived compounds: implications for the development of prevention strategies for oral and pharyngeal cancers.Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population.
P2860
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P2860
Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Relationship between interindi ...... enetic polymorphism in humans.
@ast
Relationship between interindi ...... enetic polymorphism in humans.
@en
type
label
Relationship between interindi ...... enetic polymorphism in humans.
@ast
Relationship between interindi ...... enetic polymorphism in humans.
@en
prefLabel
Relationship between interindi ...... enetic polymorphism in humans.
@ast
Relationship between interindi ...... enetic polymorphism in humans.
@en
P2093
P356
P1476
Relationship between interindi ...... genetic polymorphism in humans
@en
P2093
H Yamamoto
M Nakajima
T Yamamoto
Y Yamamoto
P356
10.1067/MCP.2001.112688
P407
P577
2001-01-01T00:00:00Z