D-24851, a novel synthetic microtubule inhibitor, exerts curative antitumoral activity in vivo, shows efficacy toward multidrug-resistant tumor cells, and lacks neurotoxicity.
about
Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stabilityStabilizing versus destabilizing the microtubules: a double-edge sword for an effective cancer treatment option?Beyond taxanes: the next generation of microtubule-targeting agentsSuprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilizationThe novel tubulin polymerization inhibitor MHPT exhibits selective anti-tumor activity against rhabdomyosarcoma in vitro and in vivoNovel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells.Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor.Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitorN-Cyclo-hexyl-2-(5-meth-oxy-1H-indol-3-yl)-2-oxoacetamide.2-(1-Ethyl-5-meth-oxy-1H-indol-3-yl)-N-(4-meth-oxy-phen-yl)-2-oxoacetamide.2-(1-Ethyl-5-meth-oxy-1H-indol-3-yl)-N-isopropyl-2-oxoacetamideN-Cyclo-hexyl-2-(5-fluoro-1H-indol-3-yl)-2-oxoacetamide.Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathwayFrom fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin polymerization inhibitorOrally bioavailable tubulin antagonists for paclitaxel-refractory cancer.An overview of tubulin inhibitors that interact with the colchicine binding site(Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.Emergence of Form from Function - Mechanical Engineering Approaches to Probe the Role of Stem Cell Mechanoadaptation in Sealing Cell FateComputational Design and Synthesis of Novel Fluoro-Analogs of Combretastatins A-4 and A-1.Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy
P2860
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P2860
D-24851, a novel synthetic microtubule inhibitor, exerts curative antitumoral activity in vivo, shows efficacy toward multidrug-resistant tumor cells, and lacks neurotoxicity.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@ast
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@en
type
label
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@ast
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@en
prefLabel
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@ast
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@en
P2093
P1433
P1476
D-24851, a novel synthetic mic ...... ells, and lacks neurotoxicity.
@en
P2093
Vanhoefer U
P304
P407
P577
2001-01-01T00:00:00Z