Expression of a novel zinc-finger cDNA, IA-1, is associated with rat AR42J cells differentiation into insulin-positive cells.
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IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylasesZinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrestIdentification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcriptionNeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system.The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the Cbl-associated protein.Mechanisms of action of glucagon-like peptide 1 in the pancreasThe zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cellsStructure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation.INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumorsMolecular processes during fat cell development revealed by gene expression profiling and functional annotation.Herpes simplex virus induces the marked up-regulation of the zinc finger transcriptional factor INSM1, which modulates the expression and localization of the immediate early protein ICP0.Functional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiationNeurogenin 3 recruits CBP co-activator to facilitate histone H3/H4 acetylation in the target gene INSM1.Glucagon-like peptide 1 agonists and the development and growth of pancreatic beta-cells.Insm1 promotes the transition of olfactory progenitors from apical and proliferative to basal, terminally dividing and neuronogenic.
P2860
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P2860
Expression of a novel zinc-finger cDNA, IA-1, is associated with rat AR42J cells differentiation into insulin-positive cells.
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@ast
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@en
type
label
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@ast
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@en
prefLabel
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@ast
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@en
P2093
P1433
P1476
Expression of a novel zinc-fin ...... n into insulin-positive cells.
@en
P2093
Mary B Breslin
Michael S Lan
P304
P356
10.1097/00006676-200203000-00004
P577
2002-03-01T00:00:00Z