Direct evidence for a predominantly exolytic processive mechanism for depolymerization of heparin-like glycosaminoglycans by heparinase I.
about
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residuesEngineering broad-spectrum digestion of polyuronides from an exolytic polysaccharide lyaseAn integrated approach using orthogonal analytical techniques to characterize heparan sulfate structureCleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparinModulations of glypican-1 heparan sulfate structure by inhibition of endogenous polyamine synthesis. Mapping of spermine-binding sites and heparanase, heparin lyase, and nitric oxide/nitrite cleavage sites.Mass spectrometric evidence for the enzymatic mechanism of the depolymerization of heparin-like glycosaminoglycans by heparinase II.Mass spectrometric and capillary electrophoretic investigation of the enzymatic degradation of heparin-like glycosaminoglycans.Sequencing of 3-O sulfate containing heparin decasaccharides with a partial antithrombin III binding site.Mode of action and subsite studies of the guluronan block-forming mannuronan C-5 epimerases AlgE1 and AlgE6Anticoagulant heparan sulfate precursor structures in F9 embryonal carcinoma cells.Structural elucidation of the tetrasaccharide pool in enoxaparin sodium.Heparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages.Heparin mapping using heparin lyases and the generation of a novel low molecular weight heparinInvestigation of the substrate specificity of K5 lyase A from K5A bacteriophageCapillary electrophoresis of complex natural polysaccharidesOn-line separations combined with MS for analysis of glycosaminoglycansNew Insights in Thrombin Inhibition Structure-Activity Relationships by Characterization of Octadecasaccharides from Low Molecular Weight Heparin.Synthetic heparin pentasaccharide depolymerization by heparinase I: molecular and biological implications.Analysis of Glycosaminoglycans Using Mass Spectrometry.'Immunosequencing' of heparan sulfate from human cell lines and rat kidney: the (GlcNS6S-IdoA2S)₃ motif, recognized by antibody NS4F5, is located towards the non-reducing end.Biochemical characterization of the chondroitinase ABC I active siteAction pattern and substrate specificity of the hyaluronan lyase from group B streptococciBiochemical analysis of the processive mechanism for epimerization of alginate by mannuronan C-5 epimerase AlgE4.Structural characterization of chondroitin/dermatan sulfate oligosaccharides from bovine aorta by capillary electrophoresis and electrospray ionization quadrupole time-of-flight tandem mass spectrometry.Four decades of structure determination by mass spectrometry: from alkaloids to heparin.Competing fragmentation processes in tandem mass spectra of heparin-like glycosaminoglycans
P2860
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P2860
Direct evidence for a predominantly exolytic processive mechanism for depolymerization of heparin-like glycosaminoglycans by heparinase I.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@ast
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@en
type
label
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@ast
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@en
prefLabel
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@ast
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@en
P2093
P2860
P356
P1476
Direct evidence for a predomin ...... saminoglycans by heparinase I.
@en
P2093
A J Rhomberg
R Sasisekharan
P2860
P304
P356
10.1073/PNAS.95.8.4182
P407
P577
1998-04-01T00:00:00Z