Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. - Wikidata - wikimedia - TriplyDB

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

http://www.wikidata.org/entity/Q33112256

about

Astrogliosis in CNS pathologies: is there a role for microglia?NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair Glial modulators as potential treatments of psychostimulant abuse Ten years of Nature Reviews Neuroscience: insights from the highly cited Pesticides, microglial NOX2, and Parkinson's disease Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1 Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease.White matter damage and systemic inflammation in Parkinson's disease.Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase Development of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b.Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity The endotoxin-induced neuroinflammation model of Parkinson's disease.HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis.Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice.Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.Transplantation of Human Neural Stem Cells in a Parkinsonian Model Exerts Neuroprotection via Regulation of the Host Microenvironment NADPH oxidases: novel therapeutic targets for neurodegenerative diseases Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for n Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress.β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway.The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase.DAP12 and CD11b contribute to the microglial-induced death of dopaminergic neurons in vitro but not in vivo in the MPTP mouse model of Parkinson's disease Dangguijakyak-San Protects against 1-Methyl-4-phenyl-1,2,3,6,-tetrahydropyridine-Induced Neuronal Damage via Anti-Inflammatory Action.Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype.Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors.The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: focus on astrocytes.The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease.Destination Brain: the Past, Present, and Future of Therapeutic Gene Delivery.Outdoor Ambient Air Pollution and Neurodegenerative Diseases: the Neuroinflammation Hypothesis.The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6.

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Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

http://www.wikidata.org/entity/Q33112256

description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Journal of Immunology

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Macrophage antigen complex-1 m ...... model of Parkinson's disease.

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Belinda Wilson

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Dan Zhang

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Donato A Di Monte

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Hao Pang

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Huiming Gao

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Jau-Shyong Hong

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Li Qian

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Syed F Ali

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W Michael Caudle

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Xiaoming Hu

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P2860

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration

NADPH oxidase: an update

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator

Microglia: a sensor for pathological events in the CNS

CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression.

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10

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Michelle L. Block

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18981141

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Parkinson's disease

positive regulation of prostaglandin-E synthase activity

Integrin alpha-M

Integrin subunit beta 2

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2759089

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