Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.
about
Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsMolecular pathogenesis of long QT syndrome type 2Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome.Endocytosis of HERG is clathrin-independent and involves arf6.Mechanism and pharmacological rescue of berberine-induced hERG channel deficiencyTranscriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioningMechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cellsStereoselective Blockage of Quinidine and Quinine in the hERG Channel and the Effect of Their Rescue Potency on Drug-Induced hERG Trafficking Defect.Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane.KChIP2 is a core transcriptional regulator of cardiac excitability.hERG quality control and the long QT syndrome.Escitalopram block of hERG potassium channels.Life-threatening cardiac arrhythmias due to drug-induced QT prolongation : A retrospective study over 6 years from a medical intensive care unit.Development of a High-Throughput Flow Cytometry Assay to Monitor Defective Trafficking and Rescue of Long QT2 Mutant hERG Channels.Suppression of hERG K current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms
P2860
Q27008208-147320EE-4195-4FCE-93E1-9F9368F74157Q28077303-9D96126A-D26A-47E3-AED6-95832F3850B4Q29994709-58AEA432-C39C-48CF-BBAF-82BE8C063670Q35083164-F629527D-F170-4DBA-A3F1-45BFA142D7C2Q36212952-2D12FF01-653B-41F9-8DBC-0BF49C8F80A5Q36283104-9E00B993-2183-4D56-BE46-AE1C4D71319DQ36675819-6186C0F5-4F9F-4AB4-936A-A9F6947CF644Q37377291-FF898B36-CDDD-4115-9BD5-88DD3EF4F2D5Q37387802-50F3B718-365B-4A7D-810C-0D0AB56F4C72Q37682779-7FA83C71-9999-4F77-8D6C-7E13BDB4BDA2Q38683556-F673BCEE-79E1-432B-AF51-272AD1171E72Q48424438-DBDC123F-A196-4808-9899-737D73EAE0D1Q53361310-263F6B3C-36C1-4185-A510-DEFAB79607F0Q55362439-F4E6FE96-ECFD-49E6-B4F1-904A4CE20823Q57095368-349C8B54-31F2-46F3-B65C-50A86097AD61
P2860
Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@ast
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@en
type
label
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@ast
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@en
prefLabel
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@ast
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@en
P2093
P2860
P356
P1476
Antidepressant-induced ubiquit ...... ardiac potassium channel hERG.
@en
P2093
Adrienne T Dennis
Dierk Thomas
Drew Nassal
Eckhard Ficker
Isabelle Deschenes
P2860
P304
34413-34425
P356
10.1074/JBC.M111.254367
P407
P577
2011-08-09T00:00:00Z