Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na(+)/bile acid cotransporter.
about
Bile acid transporters in health and diseaseApical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug targetMembrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domainsRole of the intestinal bile acid transporters in bile acid and drug dispositionStructural requirements of the human sodium-dependent bile acid transporter (hASBT): role of 3- and 7-OH moieties on binding and translocation of bile acids.Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.Inhibition requirements of the human apical sodium-dependent bile acid transporter (hASBT) using aminopiperidine conjugates of glutamyl-bile acidsMolecular switch controlling the binding of anionic bile acid conjugates to human apical sodium-dependent bile acid transporter.Why we should be vigilant: drug cytotoxicity observed with in vitro transporter inhibition studies.Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters.Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates.Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2).Pharmacophore-based discovery of ligands for drug transporters.Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups.Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in miceConserved aspartic acid residues lining the extracellular loop 1 of sodium-coupled bile acid transporter ASBT Interact with Na+ and 7alpha-OH moieties on the ligand cholestane skeleton.Organic anion uptake by hepatocytes.Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter.A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides.Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid.Planar bile acids in health and disease.
P2860
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P2860
Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na(+)/bile acid cotransporter.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@ast
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@en
type
label
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@ast
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@en
prefLabel
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@ast
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@en
P2093
P1476
Substrate specificity of the i ...... Na(+)/bile acid cotransporter.
@en
P2093
Baringhaus KH
Stengelin S
P304
P577
1999-12-01T00:00:00Z