Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.

Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.

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http://www.wikidata.org/entity/Q33184039
Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice.A self-contained enzyme activating prodrug cytotherapy for preclinical melanoma.Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: postnatal surge and organ-dependent regulation.Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.A cell-delivered and cell-activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer modelHuman carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.Synthesis, characterization, and evaluation of mPEG-SN38 and mPEG-PLA-SN38 micelles for cancer therapy.Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme.In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizesA novel microfluidic liposomal formulation for the delivery of the SN-38 camptothecin: characterization and in vitro assessment of its cytotoxic effect on two tumor cell lines
P2860

Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.

Item
http://www.wikidata.org/entity/Q33184039
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@ast
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@en
type
label
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@ast
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@en
prefLabel
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@ast
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@en
P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P921
P1433
P1476
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.
@en
P2093
P304
P31
P407
P433
P478
P577
P698
P921