Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway.
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Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol HexakisphosphateInositol 1,4,5-trisphosphate 3-kinases: functions and regulationsApoptotic effect of IP(6) was not enhanced by co-treatment with myo-inositol in prostate carcinoma PC3 cells.Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasisTumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids.Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice.Protective effect of inositol hexaphosphate against UVB damage in HaCaT cells and skin carcinogenesis in SKH1 hairless mice.Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target.The behaviour of myo-inositol hexakisphosphate in the presence of magnesium(II) and calcium(II): protein-free soluble InsP6 is limited to 49 microM under cytosolic/nuclear conditions.Effect of inositol hexaphosphate on the development of UVB-induced skin tumors in SKH1 hairless miceAn analogue of resveratrol HS-1793 exhibits anticancer activity against MCF-7 cells via inhibition of mitochondrial biogenesis gene expression.Phytic Acid: From Antinutritional to Multiple Protection Factor of Organic Systems.Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5The effect of inositol hexaphosphate on the expression of selected metalloproteinases and their tissue inhibitors in IL-1β-stimulated colon cancer cells.Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors.Inhibitors of protein kinase C sensitise multiple myeloma cells to common genotoxic drugs.Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation.Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.Dephosphorylation of myo-inositol phosphates in the in vitro intestinal Caco-2 cell model.Myo-inositol hexakisphosphate, isolated from female gametophyte tissue of loblolly pine, inhibits growth of early-stage somatic embryos.
P2860
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P2860
Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@ast
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@en
type
label
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@ast
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@en
prefLabel
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@ast
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@en
P2093
P356
P1433
P1476
Inositol hexakisphosphate bloc ...... ediated cell survival pathway.
@en
P2093
Hiroki Yoshida
Masato Hirata
Miho Matsuda
Sandra Ferry
P304
P356
10.1093/CARCIN/23.12.2031
P407
P577
2002-12-01T00:00:00Z