Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.
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Long-Term Controlled Protein Release from Poly(Ethylene Glycol) Hydrogels by Modulating Mesh Size and DegradationA hybrid protein-polymer nanoworm potentiates apoptosis better than a monoclonal antibodyIdentification and characterization of single chain anti-cocaine catalytic antibodiesExceptional amyloid beta peptide hydrolyzing activity of nonphysiological immunoglobulin variable domain scaffolds.Passive protection against anthrax by using a high-affinity antitoxin antibody fragment lacking an Fc regionTherapeutic anti-methamphetamine antibody fragment-nanoparticle conjugates: synthesis and in vitro characterization.Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging.Solubilization of native integral membrane proteins in aqueous buffer by noncovalent chelation with monomethoxy poly(ethylene glycol) (mPEG) polymers.Monodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET.A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments.Recombinant bispecific antibodies for cancer therapy.Protein-based tumor molecular imaging probes.Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2Design and activity of a murine and humanized anti-CEACAM6 single-chain variable fragment in the treatment of pancreatic cancer.Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.Antibody vectors for imaging.Product development issues for PEGylated proteins.Modulating antibody pharmacokinetics using hydrophilic polymers.PEGylation and its impact on the design of new protein-based medicines.A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy.PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting.Optimization of random PEGylation reactions by means of high throughput screening.Refolding of Aggregation-Prone ScFv Antibody Fragments Assisted by Hydrophobically Modified Poly(sodium acrylate) Derivatives.High-level production of a single chain antibody against anthrax toxin in Escherichia coli by high cell density cultivation.GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli.Evaluation of a Pretargeting Strategy for Molecular Imaging of the Prostate Stem Cell Antigen with a Single Chain Antibody.In Vivo Applications of Single Chain Fv (Variable Domain) (scFv) FragmentsProduction of PEGylated Proteins
P2860
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P2860
Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Tailoring structure-function a ...... s by site-specific PEGylation.
@ast
Tailoring structure-function a ...... s by site-specific PEGylation.
@en
type
label
Tailoring structure-function a ...... s by site-specific PEGylation.
@ast
Tailoring structure-function a ...... s by site-specific PEGylation.
@en
prefLabel
Tailoring structure-function a ...... s by site-specific PEGylation.
@ast
Tailoring structure-function a ...... s by site-specific PEGylation.
@en
P2093
P356
P1476
Tailoring structure-function a ...... s by site-specific PEGylation.
@en
P2093
Amartya Basu
Clifford Longley
David Filpula
Gerald Petti
Haleema Janjua
Karen Yang
Magda Mendez
P304
P356
10.1093/PROTEIN/GZG093
P577
2003-10-01T00:00:00Z