Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.
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Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptorsPrimary afferent activation of thermosensitive TRPV1 triggers asynchronous glutamate release at central neuronsTRPV1: a target for next generation analgesicsPhysiology and pharmacology of the vanilloid receptorThe hypocretins/orexins: integrators of multiple physiological functionsTRPV1 and SP: key elements for sepsis outcome?Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoniHypersensitivity Induced by Activation of Spinal Cord PAR2 Receptors Is Partially Mediated by TRPV1 ReceptorsMechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neuronsAnandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bedFacilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populationsSpatial temperature gradients guide axonal outgrowthTRPV1: A Potential Drug Target for Treating Various Diseases.An HSV vector system for selection of ligand-gated ion channel modulators.Direct Anandamide Activation of TRPV1 Produces Divergent Calcium and Current Responses.Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphateRole of transient receptor potential channels in cholecystokinin-induced activation of cultured vagal afferent neurons.Capsaicin induces CYP3A4 expression via pregnane X receptor and CCAAT/enhancer-binding protein β activation.TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms.TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation.'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors.Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibitionPainful pathways induced by TLR stimulation of dorsal root ganglion neuronsCannabinoid receptor-independent actions of the aminoalkylindole WIN 55,212-2 on trigeminal sensory neuronsHydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airwaysAcid-sensitive ion channels and receptorsStrain differences in the neural, behavioral, and molecular correlates of sweet and salty taste in naive, ethanol- and sucrose-exposed P and NP rats.Role of TRPV1 in the Differentiation of Mouse Embryonic Stem Cells into Cardiomyocytes.Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targets.Immortalization and characterization of a nociceptive dorsal root ganglion sensory neuronal line.N-geranyl cyclopropyl-carboximide modulates salty and umami taste in humans and animal models.New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells.Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t)Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.Mitochondrial calcium buffering contributes to the maintenance of Basal calcium levels in mouse taste cells.The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensorStructure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1)TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response.Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats.
P2860
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P2860
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@ast
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@en
type
label
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@ast
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@en
prefLabel
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@ast
Identification and characteris ...... ceptor (VR1/TRPV1) antagonist.
@en
P2093
P1433
P1476
Identification and characteris ...... eceptor (VR1/TRPV1) antagonist
@en
P2093
C H Davies
E M Soffin
J C Jerman
P304
P356
10.1016/S0028-3908(03)00305-8
P577
2004-01-01T00:00:00Z