An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
about
Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysisA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyImproved targeting of miRNA with antisense oligonucleotidesIdentifying druggable disease-modifying gene productsQuantum dots to monitor RNAi delivery and improve gene silencingsiRNA-mediated off-target gene silencing triggered by a 7 nt complementationEfficient in vivo knock-down of estrogen receptor alpha: application of recombinant adenovirus vectors for delivery of short hairpin RNA.Optimization of linear double-stranded RNA for the production of multiple siRNAs targeting hepatitis C virusRNA interference and potential therapeutic applications of short interfering RNAsSecond-generation shRNA libraries covering the mouse and human genomesSYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 proteinOff-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2A functional map of NFkappaB signaling identifies novel modulators and multiple system controls.Genome-wide screening for gene function using RNAi in mammalian cells.Complete, gene-specific siRNA libraries: production and expression in mammalian cells.Gene discovery by ribozyme and siRNA libraries.The application of RAGE and GECKO in cell-based target discovery screens.Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis.Genome-wide application of RNAi to the discovery of potential drug targets.A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of functionSpecific and nontoxic silencing in mammalian cells with expressed long dsRNAs.Generation of RNAi libraries for high-throughput screens.RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signalingRegulating gene expression with light-activated oligonucleotides.High-throughput screening using siRNA (RNAi) libraries.A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells.Efficient construction of an inverted minimal H1 promoter driven siRNA expression cassette: facilitation of promoter and siRNA sequence exchange.Generation of shRNAs from randomized oligonucleotidesRNA modulators of complex phenotypes in mammalian cells.Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.Exploration of chromatic aberration for multiplanar imaging: proof of concept with implications for fast, efficient autofocus.Quantification of lipid droplets and associated proteins in cellular models of obesity via high-content/high-throughput microscopy and automated image analysis.Unlocking the potential of the human genome with RNA interference.RNA interference for improving the outcome of islet transplantation.Functional mapping of disease susceptibility loci using cell biology.Novel small RNA expression libraries uncover hsa-miR-30b and hsa-miR-30c as important factors in anoikis resistance.Improving the efficiency of RNA interference in mammals.Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNAMultiplexing siRNAs to compress RNAi-based screen size in human cells.
P2860
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P2860
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@ast
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@en
type
label
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@ast
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@en
prefLabel
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@ast
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.
@en
P2093
P2860
P356
P1476
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
@en
P2093
Anthony Orth
Demin Zhou
Lianxing Zheng
Peter G Schultz
Sheng Ding
P2860
P304
P356
10.1073/PNAS.2136685100
P407
P50
P577
2003-12-19T00:00:00Z