Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. - Wikidata - wikimedia - TriplyDB

Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

http://www.wikidata.org/entity/Q33206447

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Lean heart: Role of leptin in cardiac hypertrophy and metabolism Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals AMPK: a cellular metabolic and redox sensor. A minireview Diabetic cardiomyopathy: signaling defects and therapeutic approaches Obesity reduces left ventricular strains, torsion, and synchrony in mouse models: a cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance study.Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation.Lipotoxicity in the heart.Is there a paradox in obesity?A new mouse model of metabolic syndrome and associated complications.Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.Rescue of cardiac leptin receptors in db/db mice prevents myocardial triglyceride accumulation Cardiac remodeling in obesity.ApoO, a novel apolipoprotein, is an original glycoprotein up-regulated by diabetes in human heart.Cardiomyopathy in congenital and acquired generalized lipodystrophy: a clinical assessment.Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPAR{alpha}/PGC1{alpha} and thermogenic glycerolipid/fatty acid cycling.Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction.Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity Dietary fat and not calcium supplementation or dairy product consumption is associated with changes in anthropometrics during a randomized, placebo-controlled energy-restriction trial.Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction Fatty heart, cardiac damage, and inflammation.Mechanisms of lipotoxicity in the cardiovascular system.AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues.Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome.The role of leptin in the control of insulin-glucose axis.Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathy Nutrient sensing and utilization: Getting to the heart of metabolic flexibility.Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.Relation of leptin to left ventricular hypertrophy (from the Multi-Ethnic Study of Atherosclerosis).Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine.Taking diabetes to heart--deregulation of myocardial lipid metabolism in diabetic cardiomyopathy.Molecular mechanisms of diabetic cardiomyopathy.Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity.Lipid metabolism and toxicity in the heart.Adipose tissue: friend or foe?An Obesity Paradox: Increased Body Mass Index Is Associated with Decreased Aortic Atherosclerosis.The relative contribution of metabolic and structural abnormalities to diastolic dysfunction in obesity.Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

http://www.wikidata.org/entity/Q33206447

description

2004 nî lūn-bûn

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2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

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Proceedings of the National Academy of Sciences of the United States of America

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Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.

@en

P2093

Byung-Hyun Park

http://www.w3.org/2001/XMLSchema#string

Daniel J Garry

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James A Richardson

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Jean E Schaffer

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Laurence Duplomb

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R Haris Naseem

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Roger H Unger

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Young Lee

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P2860

Positional cloning of the mouse obese gene and its human homologue

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis

Weight-reducing effects of the plasma protein encoded by the obese gene

Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia.

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype.

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101

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