Synthesis of tailor-made glycoconjugate mimetics of heparan sulfate that bind IFN-gamma in the nanomolar range.
about
Can we produce heparin/heparan sulfate biomimetics using "mother-nature" as the gold standard?Profiling heparin-chemokine interactions using synthetic toolsModular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies.Orthogonal sulfation strategy for synthetic heparan sulfate ligands.New glucuronic acid donors for the modular synthesis of heparan sulfate oligosaccharidesPreactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions.Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestisThe specificity of interactions between proteins and sulfated polysaccharides.Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site.Synthesis of a targeted library of heparan sulfate hexa- to dodecasaccharides as inhibitors of β-secretase: potential therapeutics for Alzheimer's disease.Divergent Synthesis of Heparan Sulfate Oligosaccharides.Strategies in synthesis of heparin/heparan sulfate oligosaccharides: 2000-present.Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies.Solid-phase synthesis of alpha-glucosamine sulfoforms with fragmentation analysis by tandem mass spectrometry.Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis.Toward automated oligosaccharide synthesis.Heparan sulfate mimicry: a synthetic glycoconjugate that recognizes the heparin binding domain of interferon-gamma inhibits the cytokine activity.Synthesis of amine-functionalized heparin oligosaccharides for the investigation of carbohydrate-protein interactions in microtiter plates.Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.Synthesis of simple heparanase substrates.First Synthesis of Heparan Sulfate Tetrasaccharides Containing both N-Acetylated and N-Unsubstituted Glucosamine-Search for Putative 10E4 Epitopes
P2860
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P2860
Synthesis of tailor-made glycoconjugate mimetics of heparan sulfate that bind IFN-gamma in the nanomolar range.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@ast
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@en
type
label
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@ast
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@en
prefLabel
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@ast
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@en
P2093
P356
P1476
Synthesis of tailor-made glyco ...... -gamma in the nanomolar range.
@en
P2093
André Lubineau
David Bonnaffé
Hugues Lortat-Jacob
Ollivier Gavard
Stéphane Sarrazin
P304
P356
10.1002/CHEM.200306063
P407
P577
2004-09-01T00:00:00Z