Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines.
about
Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLProto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosisPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersAssociation of single nucleotide polymorphisms in PIM-1 gene with the risk of Korean lung cancerTargeting Pim kinases for cancer treatment: opportunities and challengesThe PIM kinases in hematological cancersThe role of PIM1/PIM2 kinases in tumors of the male reproductive systemPim3 negatively regulates glucose-stimulated insulin secretionHepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggsEctopic over-expression of oncogene Pim-2 induce malignant transformation of nontumorous human liver cell line L02Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.The Pim protein kinases regulate energy metabolism and cell growthMining for novel candidate clock genes in the circadian regulatory networkMicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine.Pim Kinase Interacts with Nonstructural 5A Protein and Regulates Hepatitis C Virus Entry.The hepatic transcriptome in human liver diseaseConstruction and application of a zebrafish array comparative genomic hybridization platformStochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate.Pim protein kinase-3 is regulated by TNF-α and promotes endothelial cell sprouting.Roles of Pim-3, a novel survival kinase, in tumorigenesis.The PIM family of serine/threonine kinases in cancer.PIM kinases: an overview in tumors and recent advances in pancreatic cancer.PIM kinase (and Akt) biology and signaling in tumors.MiR-377 inhibits the proliferation of pancreatic cancer by targeting Pim-3.Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine.Identification of a phenanthrene derivative as a potent anticancer drug with Pim kinase inhibitory activity.Pim-3 Regulates Stemness of Pancreatic Cancer Cells via Activating STAT3 Signaling Pathway.Inflammation and stem markers association to PIM1/PIM2 kinase-induced tumors in breast and uterus.MicroRNA-216b-5p Functions as a Tumor-suppressive RNA by Targeting TPT1 in Pancreatic Cancer Cells.Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447.Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells.Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver.Pim-3 enhances melanoma cell migration and invasion by promoting STAT3 phosphorylation.Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma.
P2860
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P2860
Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@ast
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@en
type
label
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@ast
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@en
prefLabel
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@ast
Aberrant expression of serine/ ...... of human hepatoma cell lines.
@en
P2093
P2860
P356
P1476
Aberrant expression of serine/ ...... n of human hepatoma cell lines
@en
P2093
Boryana K Popivanova
Chifumi Fujii
Koichi Tsuneyama
Peirong Lu
Shuichi Kaneko
Yasunari Nakamoto
P2860
P304
P356
10.1002/IJC.20719
P577
2005-03-01T00:00:00Z