Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
about
Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathwayCaspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.The expression level of the voltage-dependent anion channel controls life and death of the cell.Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R expression at the cell surface.Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancersThe role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic.Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol.Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo.Chemical regulation of signaling pathways to programmed necrosis.Monomethylarsonous acid, but not inorganic arsenic, is a mitochondria-specific toxicant in vascular smooth muscle cells.Cytokine-induced senescence for cancer surveillance.Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.Arsenic trioxide inhibits growth of As4.1 juxtaglomerular cells via cell cycle arrest and caspase-independent apoptosis.Arsenic Induces Thioredoxin 1 and Apoptosis in Human Liver HHL-5 Cells.Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells.CD44 ligation induces apoptosis via caspase- and serine protease-dependent pathways in acute promyelocytic leukemia cells.Enhancement of Arsenic Trioxide (As(2)O(3))- Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y CellsChanging T-cell enigma: cancer killing or cancer control?Arsenic-induced cell death in liver and brain of experimental rats.Antioxidants Protect against Arsenic Induced Mitochondrial Cardio-Toxicity.Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.Antitumor activity of arsenite in combination with tetrandrine against human breast cancer cell line MDA-MB-231 in vitro and in vivo
P2860
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P2860
Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@ast
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@en
type
label
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@ast
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@en
prefLabel
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@ast
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@en
P2093
P2860
P356
P1433
P1476
Arsenic trioxide triggers a re ...... e mitochondrial death pathway.
@en
P2093
Bernd Dörken
Christian Scholz
Frank Essmann
Klaus Schulze-Osthoff
Lilian Stärck
Peter T Daniel
Thomas Wieder
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208233
P407
P577
2005-03-01T00:00:00Z
P5875
P6179
1004981590