Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt.
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Neuroprotective effect of melatonin: a novel therapy against perinatal hypoxia-ischemiaRadiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposureMelatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in mice.Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice.The antiapoptotic activity of melatonin in neurodegenerative diseases.Melatonin Attenuates Pulmonary Hypertension in Chronically Hypoxic Rats.Melatonin combats molecular terrorism at the mitochondrial level.The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: a review of rtPA neurotoxicitymtDNA T8993G mutation-induced F1F0-ATP synthase defect augments mitochondrial dysfunction associated with hypoxia/reoxygenation: the protective role of melatoninEffects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculationMelatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway.Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration.Antioxidants and free radical scavengers do not consistently delay seizure onset in animal models of acute seizures.Melatonin and ischemia-reperfusion injury of the brain.Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stagesMelatonin in the management of perinatal hypoxic-ischemic encephalopathy: light at the end of the tunnel?Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms.The antioxidative property of melatonin against brain ischemia.Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin.Melatonin inhibits matrix metalloproteinase-9 (MMP-9) activation in the lipopolysaccharide (LPS)-stimulated RAW 264.7 and BV2 cells and a mouse model of meningitis.Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice.Melatonin decreases nitric oxide production, inducible nitric oxide synthase expression and lipid peroxidation induced by Venezuelan encephalitis equine virus in neuroblastoma cell cultures.Hypothermia in cardiogenic shock reduces systemic t-PA release.Melatonin decreases nitric oxide production and lipid peroxidation and increases interleukin-1 beta in the brain of mice infected by the Venezuelan equine encephalomyelitis virus.Melatonin provides neuroprotection by reducing oxidative stress and HSP70 expression during chronic cerebral hypoperfusion in ovariectomized rats.Melatonin prevents the injury-induced decline of Akt/forkhead transcription factors phosphorylation.Chronic and acute melatonin effects in gerbil global forebrain ischemia: long-term neural and behavioral outcome.Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice.Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats.Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia.Systemic and transdermal melatonin administration prevents neuropathology in response to perinatal asphyxia in newborn lambs.
P2860
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P2860
Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@ast
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@en
type
label
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@ast
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@en
prefLabel
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@ast
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@en
P2093
P1476
Tissue-plasminogen activator-i ...... latonin: role of iNOS and Akt.
@en
P2093
Claudio L Bassetti
Dirk M Hermann
Ertugrul Kilic
Russel J Reiter
Ulkan Kilic
P304
P356
10.1111/J.1600-079X.2005.00228.X
P577
2005-09-01T00:00:00Z