Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication.

Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication.

Item
http://www.wikidata.org/entity/Q33225026
The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP sheddingParallel screening of wild-type and drug-resistant targets for anti-resistance neuraminidase inhibitorsSuramin inhibits Hsp104 ATPase and disaggregase activityFrom high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.Prion protein-specific antibodies-development, modes of action and therapeutics applicationSelective re-routing of prion protein to proteasomes and alteration of its vesicular secretion prevent PrP(Sc) formation.A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.Recent advances in prion chemotherapeutics.Therapeutic approaches for prion disorders.Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins.The potential of mesenchymal stem cell in prion research.Misfolding leads the way to unraveling signaling pathways in the pathophysiology of prion diseases.Exploring Anti-Prion Glyco-Based and Aromatic Scaffolds: A Chemical Strategy for the Quality of Life.Inhibition of cholesterol recycling impairs cellular PrP(Sc) propagation.Hemin interactions and alterations of the subcellular localization of prion protein.Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins.Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases.
P2860

Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication.

Item
http://www.wikidata.org/entity/Q33225026
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@ast
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@en
type
label
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@ast
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@en
prefLabel
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@ast
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Charged bipolar suramin deriva ...... and inhibit PrPSc replication.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921