Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2.
about
Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathwaysCharacterization of the human sulfatase Sulf1 and its high affinity heparin/heparan sulfate interaction domainDirect detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88Functional consequences of the subdomain organization of the sulfsSulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinomaHeparan sulphate synthetic and editing enzymes in ovarian cancerGene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativityPathophysiology of heparan sulphate: many diseases, few drugsEngineering of routes to heparin and related polysaccharidesThe SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repairWT1-dependent sulfatase expression maintains the normal glomerular filtration barrierActivation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regenerationSulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting FunctionsExtracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cellsSubstrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate.Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry.Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts.Regulation of intracellular signaling by extracellular glycan remodeling.Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signalingGlycomics analysis of mammalian heparan sulfates modified by the human extracellular sulfatase HSulf2.Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches.Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation.Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in miceExpression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell nicheSULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis.Enzymatic placement of 6-O-sulfo groups in heparan sulfateNew negative feedback regulators of Egfr signaling in Drosophila.Proteoglycans in host-pathogen interactions: molecular mechanisms and therapeutic implicationsEndothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.The role of Drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation.Molecular structure of heparan sulfate from Spalax. Implications of heparanase and hypoxia.Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt.Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer.The association of arylendosulfatase 1 (SULF1) gene polymorphism with recurrent miscarriage.
P2860
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P2860
Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@ast
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@en
type
label
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@ast
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@en
prefLabel
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@ast
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@en
P2860
P50
P356
P1476
Substrate specificity and doma ...... sulfatases, QSulf1 and QSulf2.
@en
P2093
Charles P Emerson
P2860
P304
P356
10.1074/JBC.M511902200
P407
P577
2005-12-23T00:00:00Z