Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
about
Modeling the within-host dynamics of HIV infectionInvestigating CTL mediated killing with a 3D cellular automatonA comparison of elasticities of viral levels to specific immune response mechanisms in human immunodeficiency virus infection.Vaccination and timing influence SIV immune escape viral dynamics in vivo.Dynamics of immune escape during HIV/SIV infection.The evolutionary selective advantage of HIV-1 escape variants and the contribution of escape to the HLA-associated risk of AIDS progression.Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequencesWithin-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV InfectionTransmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infectionPersistence of viral infection despite similar killing efficacy of antiviral CD8(+) T cells during acute and chronic phases of infection.Virus replication strategies and the critical CTL numbers required for the control of infection.Inferring HIV Escape Rates from Multi-Locus Genotype Data.Protective efficacy of individual CD8+ T cell specificities in chronic viral infectionFitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infectionThe route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations.In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaquesUnderstanding the failure of CD8+ T-cell vaccination against simian/human immunodeficiency virus.Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL EscapesEstimating the effectiveness of simian immunodeficiency virus-specific CD8+ T cells from the dynamics of viral immune escapeCD4+ target cell availability determines the dynamics of immune escape and reversion in vivo.Computational inference methods for selective sweeps arising in acute HIV infection.The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses.Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN).Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infectionNotwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells.Antibody escape kinetics of equine infectious anemia virus infection of horses.Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants.Kinetics of HIV-Specific CTL Responses Plays a Minimal Role in Determining HIV Escape Dynamics.Impaired immune evasion in HIV through intracellular delays and multiple infection of cells.Time Intervals in Sequence Sampling, Not Data Modifications, Have a Major Impact on Estimates of HIV Escape Rates.
P2860
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P2860
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
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2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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name
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@ast
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@en
type
label
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@ast
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@en
prefLabel
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@ast
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@en
P2860
P1476
Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection.
@en
P2093
Rob J De Boer
P2860
P356
10.1371/JOURNAL.PCBI.0020024
P577
2006-03-31T00:00:00Z