Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
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In-vivo biodistribution and safety of 99mTc-LLP2A-HYNIC in canine non-Hodgkin lymphomaVery late antigen-4 (α(4)β(1) Integrin) targeted PET imaging of multiple myelomaOptical imaging probes in oncologySelf-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammationHigh-Throughput Approaches to the Development of Molecular Imaging Agents.Revealing protein structures in solid-phase peptide synthesis by 13C solid-state NMR: evidence of excessive misfolding for Alzheimer's β.Micropatterned photodegradable hydrogels for the sorting of microbeads and cells.Cardiovascular molecular imaging: focus on clinical translationFlow cytometry for drug discovery, receptor pharmacology and high-throughput screeningScreening of a one bead-one compound combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cellsNear-infrared optical imaging in glioblastoma xenograft with ligand-targeting alpha 3 integrin.Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method.Development of hydrogel TentaGel shell-core beads for ultrahigh throughput solution-phase screening of encoded OBOC combinatorial small molecule libraries.On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.High-throughput in vivo screening of targeted molecular imaging agents.Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beadsPotential of phage-displayed peptide library technology to identify functional targeting peptidesDevelopment and characterization of 5 canine B-cell lymphoma cell linesJeffamine derivatized TentaGel beads and poly(dimethylsiloxane) microbead cassettes for ultrahigh-throughput in situ releasable solution-phase cell-based screening of one-bead-one-compound combinatorial small molecule librariesEffect of small-molecule-binding affinity on tumor uptake in vivo: a systematic study using a pretargeted bispecific antibodyThe use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handleIdentification of a bladder cancer-specific ligand using a combinatorial chemistry approachHPMA copolymers: origins, early developments, present, and future.Effect of Fe(3)O(4)-magnetic nanoparticles on acute exercise enhanced KCNQ(1) expression in mouse cardiac muscleThe rise, fall and reinvention of combinatorial chemistry.Macromolecular therapeuticsSmall-molecule-modified surfaces engage cells through the αvβ3 integrin.Affinity of the alpha4-beta1 integrin-targeting peptide LLP2A to canine lymphoma.On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands.On-bead screens sample narrower affinity ranges of protein-ligand interactions compared to equivalent solution assays.Discovery of specific ligands for oral squamous carcinoma to develop anti-cancer drug loaded precise targeting nanotherapeutics.Targeting canine bladder transitional cell carcinoma with a human bladder cancer-specific ligandImmobilized OBOC combinatorial bead array to facilitate multiplicative screening.Design of peptide affinity ligands for S-protein: a comparison of combinatorial and de novo design strategies.The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles.Integrin targeted delivery of radiotherapeutics.A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions.Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.Synthesis, characterization, and biological activity of poly(arginine)-derived cancer-targeting peptides in HepG2 liver cancer cells.Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin.
P2860
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P2860
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@ast
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@en
type
label
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@ast
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@en
prefLabel
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@ast
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@en
P2093
P356
P1476
Combinatorial chemistry identi ...... rin for in vivo tumor imaging.
@en
P2093
P2888
P304
P356
10.1038/NCHEMBIO798
P577
2006-06-11T00:00:00Z