Improving solubility and refolding efficiency of human V(H)s by a novel mutational approach.

Improving solubility and refolding efficiency of human V(H)s by a novel mutational approach.

Item
http://www.wikidata.org/entity/Q33257515
Nanobodies and recombinant binders in cell biologyNanobodies as Probes for Protein Dynamics in Vitro and in Cells.Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points.Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli.Engineered Autonomous Human Variable DomainsSingle domain antibodies for the knockdown of cytosolic and nuclear proteins.Antibody light chain variable domains and their biophysically improved versions for human immunotherapy.Molecular dynamics simulations and docking enable to explore the biophysical factors controlling the yields of engineered nanobodies.Ultra scale-down characterization of the impact of conditioning methods for harvested cell broths on clarification by continuous centrifugation-Recovery of domain antibodies from rec E. coli.Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions.Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human VH/VL Single-Domain Antibodies from In Vitro Display Libraries.Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy.The Versatility of Framework Regions of Chicken VH and VL to Mutations.
P2860

Improving solubility and refolding efficiency of human V(H)s by a novel mutational approach.

Item
http://www.wikidata.org/entity/Q33257515
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Improving solubility and refolding efficiency of human V
@nl
Improving solubility and refol ...... y a novel mutational approach.
@ast
Improving solubility and refol ...... y a novel mutational approach.
@en
type
label
Improving solubility and refolding efficiency of human V
@nl
Improving solubility and refol ...... y a novel mutational approach.
@ast
Improving solubility and refol ...... y a novel mutational approach.
@en
prefLabel
Improving solubility and refolding efficiency of human V
@nl
Improving solubility and refol ...... y a novel mutational approach.
@ast
Improving solubility and refol ...... y a novel mutational approach.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Improving solubility and refol ...... y a novel mutational approach.
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921