Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulum-retention signal is N-glycosylated homogeneously throughout the plant with mostly high-mannose-type N-glycans.
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Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco.Anti-infective immunoadhesins from plants.Biochemical Characterization of Human Anti-Hepatitis B Monoclonal Antibody Produced in the Microalgae Phaeodactylum tricornutumGrowth phase-dependent expression of proteins with decreased plant-specific N-glycans and immunogenicity in tobacco BY2 cells.Inhibition of human MCF-7 breast cancer cells and HT-29 colon cancer cells by rice-produced recombinant human insulin-like growth binding protein-3 (rhIGFBP-3).Aberrant localization and underglycosylation of highly accumulating single-chain Fv-Fc antibodies in transgenic Arabidopsis seeds.A human anti-Pseudomonas aeruginosa serotype O6ad immunoglobulin G1 expressed in transgenic tobacco is capable of recruiting immune system effector function in vitro.Generation of glyco-engineered BY2 cell lines with decreased expression of plant-specific glycoepitopes.SNAREs: cogs and coordinators in signaling and development.Plant-based strategies aimed at expressing HIV antigens and neutralizing antibodies at high levels. Nef as a case studyThe use of plants for the production of therapeutic human peptides.Trafficking of endoplasmic reticulum-retained recombinant proteins is unpredictable in Arabidopsis thaliana.Comparative in vitro and experimental in vivo studies of the anti-epidermal growth factor receptor antibody nimotuzumab and its aglycosylated form produced in transgenic tobacco plants.Tobacco seeds as efficient production platform for a biologically active anti-HBsAg monoclonal antibody.Engineering of a sialic acid synthesis pathway in transgenic plants by expression of bacterial Neu5Ac-synthesizing enzymes.Localization of rabies virus glycoprotein into the endoplasmic reticulum produces immunoprotective antigen.Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans.The B cell death function of obinutuzumab-HDEL produced in plant (Nicotiana benthamiana L.) is equivalent to obinutuzumab produced in CHO cells.Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits.A KDEL-tagged monoclonal antibody is efficiently retained in the endoplasmic reticulum in leaves, but is both partially secreted and sorted to protein storage vacuoles in seeds
P2860
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P2860
Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulum-retention signal is N-glycosylated homogeneously throughout the plant with mostly high-mannose-type N-glycans.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@ast
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@en
type
label
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@ast
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@en
prefLabel
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@ast
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@en
P2093
P2860
P921
P1476
Plant-derived mouse IgG monocl ...... y high-mannose-type N-glycans.
@en
P2093
Ada Triguero
Chun-Ting Yuen
Gleysin Cabrera
José A Cremata
Jun Wheeler
Nadia I Ramírez
P2860
P304
P356
10.1111/J.1467-7652.2005.00137.X
P577
2005-07-01T00:00:00Z