At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction.
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Human T regulatory cell therapy: take a billion or so and call me in the morningApoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.The type of responder T-cell has a significant impact in a human in vitro suppression assay.Apoptosis of purified CD4+ T cell subsets is dominated by cytokine deprivation and absence of other cells in new onset diabetic NOD mice.Impaired thymic export and apoptosis contribute to regulatory T-cell defects in patients with chronic heart failureInteraction between Treg apoptosis pathways, Treg function and HLA risk evolves during type 1 diabetes pathogenesisFoxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.CD28⁻ CD8⁺ T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes.Evaluation of T regulatory cell apoptosis in children with newly recognized type 1 diabetes mellitus.Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus.Can we vaccinate against Type 1 diabetes?Impaired thymic export and increased apoptosis account for regulatory T cell defects in patients with non-ST segment elevation acute coronary syndrome.Function of Treg Cells Decreased in Patients With Systemic Lupus Erythematosus Due To the Effect of ProlactinRapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cellsNatural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis.Immune modulation in humans: implications for type 1 diabetes mellitus.Alteration of regulatory T cells in type 1 diabetes mellitus: a comprehensive review.Mechanisms of autoimmunity in the non-obese diabetic mouse: effector/regulatory cell equilibrium during peak inflammation.Restoring Regulatory T Cells in Type 1 Diabetes.Regulatory T cell dysfunction in type 1 diabetes: what's broken and how can we fix it?CD25high T cells with a prolonged survival inhibit development of diabetes.Regulatory T cells in children with recently diagnosed type 1 diabetes.Low frequency of GITR+ T cells in ex vivo and in vitro expanded Treg cells from type 1 diabetic patients.Low frequency of regulatory T cells in the peripheral blood of children with type 1 diabetes diagnosed under the age of five.Genetic association of HLA DQB1 with CD4+CD25+(high) T-cell apoptosis in type 1 diabetes.Recent insights into CD4+T-cell specificity and function in Type 1 diabetes
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P2860
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction.
description
2007 nî lūn-bûn
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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@ast
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@en
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@nl
type
label
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@ast
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@en
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@nl
prefLabel
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@ast
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@en
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@nl
P2093
P2860
P1433
P1476
At-risk and recent-onset type ...... the CD4+CD25+ T-cell fraction.
@en
P2093
Hope Albertz
Huoy-Jii Khoo
Jeffrey Woodliff
Jill Waukau
Marilyn Koppen
Parthav Jailwala
Ramin Alemzadeh
Sanja Glisic-Milosavljevic
Soumitra Ghosh
Srikanta Jana
P2860
P356
10.1371/JOURNAL.PONE.0000146
P407
P577
2007-01-03T00:00:00Z