A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
about
Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family CoronaviridaeDevelopment of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genesAnimal models for SARS and MERS coronavirusesAnimal models of respiratory syncytial virus infection and diseaseMolecular pathology of emerging coronavirus infectionsModeling host genetic regulation of influenza pathogenesis in the collaborative crossA new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivoAnimal models of Middle East respiratory syndrome coronavirus infectionSevere acute respiratory syndrome coronavirus as an agent of emerging and reemerging infectionVirus-infected alveolar epithelial cells direct neutrophil chemotaxis and inhibit their apoptosisEvidence supporting a zoonotic origin of human coronavirus strain NL63A decade after SARS: strategies for controlling emerging coronavirusesRapid generation of a mouse model for Middle East respiratory syndrome.The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis.Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variantA comprehensive collection of systems biology data characterizing the host response to viral infection.Gain-of-Function Research and the Relevance to Clinical Practice.Moving beyond metagenomics to find the next pandemic virusRecent insights into pulmonary repair following virus-induced inflammation of the respiratory tract.Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection.The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death.Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines.MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice.SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesisInfidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection.Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infectionCoronaviruses post-SARS: update on replication and pathogenesis.Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease.Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice.Systems approaches to Coronavirus pathogenesis.Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaquesRat respiratory coronavirus infection: replication in airway and alveolar epithelial cells and the innate immune response.T cell epitope specificity and pathogenesis of mouse hepatitis virus-1-induced disease in susceptible and resistant hosts.Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation.The spike protein of SARS-CoV--a target for vaccine and therapeutic development.
P2860
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P2860
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@ast
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@en
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@nl
type
label
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@ast
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@en
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@nl
prefLabel
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@ast
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@en
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@nl
P2093
P2860
P50
P1433
P1476
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
@en
P2093
Aaron Cheng
Boyd Yount
Brian D Herman
Damon Deming
Gillian L Genrich
Leatrice Vogel
Tim Sheahan
P2860
P356
10.1371/JOURNAL.PPAT.0030005
P577
2007-01-01T00:00:00Z