Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries. - Wikidata - wikimedia - TriplyDB

Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries.

Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries.

http://www.wikidata.org/entity/Q33274792

about

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro IVIG-bound IgG and IgM cloned by phage display from a healthy individual reveal the same restricted germ-line gene origin as in autoimmune thrombocytopenia.Efficient generation of respiratory syncytial virus (RSV)-neutralizing human MoAbs via human peripheral blood lymphocyte (hu-PBL)-SCID mice and scFv phage display libraries.Restricted VH3 gene usage in phage-displayed Fab that are selected by intravenous immunoglobulin.Genetic origin of IgG antibodies cloned by phage display and anti-idiotypic panning from three patients with autoimmune thrombocytopenia.Production of human monoclonal antibodies in SCID mouse.Protein engineering of antibodies.Possible presence of enhancing antibodies in idiopathic thrombocytopenic purpura.Platelet-reactive IgG antibodies cloned by phage display and panning with IVIG from three patients with autoimmune thrombocytopenia.Paradoxical enhancement of tumor growth in mice with severe combined immunodeficiency which produce a human immunoglobulin G reactive against tumor cells.Mining human antibody repertoires.Role of interleukin-4 in human immunoglobulin E formation in hu-PBL-SCID mice.Development and characterization of anti-idiotype based peptide and DNA vaccines which mimic the capsular polysaccharide of Neisseria meningitidis serogroup C.Infection of SCID mice with Mycobacterium leprae and control with antigen-activated "immune" human peripheral blood mononuclear cells Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice.Characterization of hu-PBL-SCID mice with high human immunoglobulin serum levels and graft-versus-host disease.Combinatorial autoantibodies to dihydrolipoamide acetyltransferase, the major autoantigen of primary biliary cirrhosis.Human monoclonal antibodies: achievement and potential.Medical applications of single-chain antibodies.SCID-Hu mice immunized with a pneumococcal vaccine produce specific human antibodies and show increased resistance to infection.Recent advances in the study of human antibody responses to influenza virus using optimized human hybridoma approaches.Hepatitis B virus core antigen binds and activates naive human B cells in vivo: studies with a human PBL-NOD/SCID mouse model.Generation of human monoclonal antibodies recognising membranous antigens of the lung adenocarcinoma cell line A549 using an AMeX immunohistostaining method.Autoimmunity versus allo- and xeno-reactivity in SCID mice.Recombinant antibody technology: its advent and advances.Engraftment of myasthenia gravis thymocytes into severe combined immunodeficiency (SCID) mice.The use of SCID mice in biotechnology and as a model for human disease.Kawasaki disease: update on diagnosis, treatment, and a still controversial etiology.Production of human immunoglobulin G reactive against human cancer in tumor-bearing mice with severe combined immunodeficiency reconstituted with human splenic tissues.Mono- and bivalent antibody fragments produced in Escherichia coli: engineering, folding and antigen binding.E2F-1-deficient NOD/SCID mice developed showing decreased saliva production.Antigen-specific T cell responses in human peripheral blood leucocyte (hu-PBL)-mouse chimera conditioned with radiation and an antibody directed against the mouse IL-2 receptor beta-chain.Mouse strain and conditioning regimen determine survival and function of human leucocytes in immunodeficient mice.Murine IL-2 receptor beta chain blockade improves human leukocyte engraftment in SCID mice.Intranasal administration of peptide vaccine protects human/mouse radiation chimera from influenza infection.Human tonsil implants xenotransplanted in SCID mice display broad lymphocytic diversity and cellular activation profile similar to those in the original lymphoid organ.

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P2860

Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries.

http://www.wikidata.org/entity/Q33274792

description

1992 nî lūn-bûn

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1992 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1992 թվականի հունվարին հրատարակված գիտական հոդված

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1992年の論文

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1992年論文

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name

Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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Immunization of hu-PBL-SCID mi ...... rough combinatorial libraries.

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