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Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin.Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing lossL-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression.The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats.
P50
description
onderzoeker
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name
Karin Rohbock
@ast
Karin Rohbock
@en
Karin Rohbock
@es
Karin Rohbock
@nl
Karin Rohbock
@sl
type
label
Karin Rohbock
@ast
Karin Rohbock
@en
Karin Rohbock
@es
Karin Rohbock
@nl
Karin Rohbock
@sl
prefLabel
Karin Rohbock
@ast
Karin Rohbock
@en
Karin Rohbock
@es
Karin Rohbock
@nl
Karin Rohbock
@sl