Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome. - Wikidata - wikimedia - TriplyDB

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

http://www.wikidata.org/entity/Q33275830

about

Delayed and accelerated aging share common longevity assurance mechanisms A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality SIRT6 in DNA repair, metabolism and ageing Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms Diseases associated with defective responses to DNA damage Somatic mutations in aging, cancer and neurodegeneration Mammalian transcription-coupled excision repair Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice Systemic DNA damage responses in aging and diseases Quality control mechanisms in cellular and systemic DNA damage responses UVSSA and USP7, a new couple in transcription-coupled DNA repair Impact of genomic damage and ageing on stem cell function Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice The ERCC6 gene and age-related macular degeneration An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function.The p53 network: cellular and systemic DNA damage responses in aging and cancer.Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1.Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice A C. elegans homolog of the Cockayne syndrome complementation group A gene.Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1.Changes in DNA repair during aging.Lifespan extension by dietary intervention in a mouse model of Cockayne syndrome uncouples early postnatal development from segmental progeria.Metabolism, genomics, and DNA repair in the mouse aging liver.Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage.DNA damage and ageing: new-age ideas for an age-old problem DNA repair mechanisms in cancer development and therapy Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1.

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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

http://www.wikidata.org/entity/Q33275830

description

2007 nî lūn-bûn

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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2007年の論文

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Impaired genome maintenance su ...... n mice with Cockayne syndrome.

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Impaired genome maintenance su ...... n mice with Cockayne syndrome.

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Impaired genome maintenance su ...... n mice with Cockayne syndrome.

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Impaired genome maintenance su ...... n mice with Cockayne syndrome.

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Impaired genome maintenance su ...... n mice with Cockayne syndrome.

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Conny van Oostrom

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Errol C Friedberg

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Gijsbertus T J van der Horst

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Harry van Steeg

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Ingrid van der Pluijm

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James R Mitchell

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Jan H J Hoeijmakers

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Jan de Wit

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Karin E M Diderich

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Kiyoji Tanaka

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P2860

Aging and gene expression in the primate brain

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3

Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice

Aging: a theory based on free radical and radiation chemistry

Aging and genome maintenance: lessons from the mouse?

GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo

Characterization of defective nucleotide excision repair in XPC mutant mice

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage

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