Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition. - Wikidata - wikimedia - TriplyDB

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.

http://www.wikidata.org/entity/Q33282784

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PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation PARPs and the DNA damage response Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1."Back to a false normality": new intriguing mechanisms of resistance to PARP inhibitors The effect of acute dose charge particle radiation on expression of DNA repair genes in mice.Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition Small fragment homologous replacement: evaluation of factors influencing modification efficiency in an eukaryotic assay system.Development of synthetic lethality anticancer therapeutics.TGFβ induces "BRCAness" and sensitivity to PARP inhibition in breast cancer by regulating DNA-repair genes Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.Role of Apoptotic Proteins in REC-2006 Mediated Radiation Protection in Hepatoma Cell Lines.The ups and downs of DNA repair biomarkers for PARP inhibitor therapies The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest.Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy.Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability Regulation of chromatin structure by poly(ADP-ribosyl)ation.Low-dose radiation hyper-radiosensitivity in multicellular tumour spheroids Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue.Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors.Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90 Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM.PARP1 regulates the protein stability and proapoptotic function of HIPK2.SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.DNA damage response is hijacked by human papillomaviruses to complete their life cycle The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.ATM protein kinase: the linchpin of cellular defenses to stress.The role of PARP1 in the DNA damage response and its application in tumor therapy.H2AX a promising biomarker for lung cancer: a review.A review of the use of melatonin in ulcerative colitis: experimental evidence and new approaches.Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1.In vitro genotoxicity of airborne Ni-NP in air-liquid interface.

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Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.

http://www.wikidata.org/entity/Q33282784

description

2007 nî lūn-bûn

@nan

2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի ապրիլին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Interaction between ATM and PA ...... cells through PARP inhibition.

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Andreína Peralta

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David Martín-Oliva

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F Javier Oliver

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Gilbert de Murcia

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Josiane Menissier-de Murcia

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José Antonio Muñoz-Gámez

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Maria Teresa Valenzuela

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Mariano Ruiz de Almodóvar

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Rocío Aguilar-Quesada

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Rosa Quiles-Pérez

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P2860

Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

PARP-1, a determinant of cell survival in response to DNA damage

ATM: genome stability, neuronal development, and cancer cross paths

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Cell cycle checkpoint signaling through the ATM and ATR kinases

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Rocío Aguilar-Quesada

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