Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice.
about
RTX proteins: a highly diverse family secreted by a common mechanismMultifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of VibriosMechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxinMARTX toxins as effector delivery platformsVibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in miceVibrio vulnificus rtxE is important for virulence, and its expression is induced by exposure to host cells.Allosteric regulation of protease activity by small molecules.Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins.SOLiD sequencing of four Vibrio vulnificus genomes enables comparative genomic analysis and identification of candidate clade-specific virulence genesDirect interaction between quorum-sensing regulator SmcR and RNA polymerase is mediated by integration host factor to activate vvpE encoding elastase in Vibrio vulnificus.Regulation of cytotoxicity by quorum-sensing signaling in Vibrio vulnificus is mediated by SmcR, a repressor of hlyU.Additive function of Vibrio vulnificus MARTX(Vv) and VvhA cytolysins promotes rapid growth and epithelial tissue necrosis during intestinal infection.Characterization of a novel ArsR-like regulator encoded by Rv2034 in Mycobacterium tuberculosisVibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infectionMonoclonal antibodies against Vibrio vulnificus RtxA1 elicit protective immunity through distinct mechanisms.Genotype is correlated with but does not predict virulence of Vibrio vulnificus biotype 1 in subcutaneously inoculated, iron dextran-treated miceGenetic Determinants of Virulence in the Marine Fish Pathogen Vibrio anguillarum.Identification and characterization of a novel serine protease, VvpS, that contains two functional domains and is essential for autolysis of Vibrio vulnificusAutoproteolytic activation of bacterial toxins.Multipurpose assessment for the quantification of Vibrio spp. and total bacteria in fish and seawater using multiplex real-time polymerase chain reaction.Functional characterization of EpsC, a component of the type II secretion system, in the pathogenicity of Vibrio vulnificusRole of AcsR in expression of the acetyl-CoA synthetase gene in Vibrio vulnificus.Cooperative regulation of the Vibrio vulnificus nan gene cluster by NanR protein, cAMP receptor protein, and N-acetylmannosamine 6-phosphateHomodimerization and binding of specific domains to the target DNA are essential requirements for HlyU to regulate expression of the virulence gene rtxA1, encoding the repeat-in-toxin protein in the human pathogen Vibrio vulnificusSite-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain.A consensus sequence for binding of SmcR, a Vibrio vulnificus LuxR homologue, and genome-wide identification of the SmcR regulonDistinct roles of the repeat-containing regions and effector domains of the Vibrio vulnificus multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin.An Enriched European Eel Transcriptome Sheds Light upon Host-Pathogen Interactions with Vibrio vulnificus.Identification and characterization of a novel outer membrane protein receptor required for hemin utilization in Vibrio vulnificus.Genotypic Diversity and Population Structure of Vibrio vulnificus Strains Isolated in Taiwan and Korea as Determined by Multilocus Sequence Typing.Emergence of a virulent clade of Vibrio vulnificus and correlation with the presence of a 33-kilobase genomic island.Induced autoprocessing of the cytopathic Makes caterpillars floppy-like effector domain of the Vibrio vulnificus MARTX toxin.The Makes Caterpillars Floppy (MCF)-Like Domain of Vibrio vulnificus Induces Mitochondrion-Mediated ApoptosisThe Effector Domain Region of the Vibrio vulnificus MARTX Toxin Confers Biphasic Epithelial Barrier Disruption and Is Essential for Systemic Spread from the IntestineMARTX, multifunctional autoprocessing repeats-in-toxin toxins.Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells.Vibrio vulnificus VvpE inhibits mucin 2 expression by hypermethylation via lipid raft-mediated ROS signaling in intestinal epithelial cellsA common virulence plasmid in biotype 2 Vibrio vulnificus and its dissemination aided by a conjugal plasmid.Coordinate regulation of Salmonella pathogenicity island 1 (SPI1) and SPI4 in Salmonella enterica serovar TyphimuriumThe regulator HlyU, the repeat-in-toxin gene rtxA1, and their roles in the pathogenesis of Vibrio vulnificus infections
P2860
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P2860
Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Identification and characteriz ...... n vitro and virulence in mice.
@ast
Identification and characteriz ...... n vitro and virulence in mice.
@en
Identification and characteriz ...... n vitro and virulence in mice.
@nl
type
label
Identification and characteriz ...... n vitro and virulence in mice.
@ast
Identification and characteriz ...... n vitro and virulence in mice.
@en
Identification and characteriz ...... n vitro and virulence in mice.
@nl
prefLabel
Identification and characteriz ...... n vitro and virulence in mice.
@ast
Identification and characteriz ...... n vitro and virulence in mice.
@en
Identification and characteriz ...... n vitro and virulence in mice.
@nl
P2093
P1476
Identification and characteriz ...... in vitro and virulence in mice
@en
P2093
Byoung Sik Kim
Byung Cheol Lee
Jeong Hyun Lee
Myung Won Kim
Sang Ho Choi
Seung Min Kim
Tae Sung Kim
P304
P577
2007-04-01T00:00:00Z