Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions
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Systematic single-cell analysis of Pichia pastoris reveals secretory capacity limits productivityOpen access to sequence: browsing the Pichia pastoris genome.Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays.The effect of hypoxia on the lipidome of recombinant Pichia pastoris.Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris.Comprehensive structural annotation of Pichia pastoris transcriptome and the response to various carbon sources using deep paired-end RNA sequencing.High-temperature cultivation of recombinant Pichia pastoris increases endoplasmic reticulum stress and decreases production of human interleukin-10.Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1' site.GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastorisDifferential Expression of Laccase Genes in Pleurotus ostreatus and Biochemical Characterization of Laccase Isozymes Produced in Pichia pastoris.Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes.Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview.TRAC in high-content gene expression analysis: applications in microbial population studies, process biotechnology and biomedical research.Sense and nonsense from a systems biology approach to microbial recombinant protein production.Bioprocess monitoring by marker gene analysis.Improving the secretory production of the heterologous protein in Pichia pastoris by focusing on protein folding.Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris.Effects of co-overexpression of secretion helper factors on the secretion of a HSA fusion protein (IL2-HSA) in Pichia pastoris.Expression of rabies virus glycoprotein in the methylotrophic yeast Pichia pastoris.Carbon metabolism limits recombinant protein production in Pichia pastoris.Thermal adaptability of Kluyveromyces marxianus in recombinant protein productionEffects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger.Quantitative Metabolomics and Instationary 13C-Metabolic Flux Analysis Reveals Impact of Recombinant Protein Production on Trehalose and Energy Metabolism in Pichia pastorisDecrease of UPR- and ERAD-related proteins in Pichia pastoris during methanol-induced secretory insulin precursor production in controlled fed-batch cultures.Optimization of production of the anti-keratin 8 single-chain Fv TS1-218 in Pichia pastoris using design of experiments.Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel 34S labeling procedure.Biomarkers to evaluate the effects of temperature and methanol on recombinant Pichia pastoris.Investigating the physiological response of Pichia (Komagataella) pastoris GS115 to the heterologous expression of misfolded proteins using chemostat cultures.Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes.A proteomic analysis of the Pichia pastoris secretome in methanol-induced cultures.Systems biotechnology for protein production in Pichia pastoris.Designing a fully automated multi-bioreactor plant for fast DoE optimization of pharmaceutical protein production.A comparative study of glycerol and sorbitol as co-substrates in methanol-induced cultures of Pichia pastoris: temperature effect and scale-up simulation.Activation of the unfolded protein response in Pichia pastoris requires splicing of a HAC1 mRNA intron and retention of the C-terminal tail of Hac1p.Influence of growth temperature on the production of antibody Fab fragments in different microbes: a host comparative analysis.Comparison of Yeasts as Hosts for Recombinant Protein Production.Fate of the UPR marker protein Kar2/Bip and autophagic processes in fed-batch cultures of secretory insulin precursor producing Pichia pastoris
P2860
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P2860
Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Monitoring of transcriptional ...... protein production conditions
@ast
Monitoring of transcriptional ...... protein production conditions
@en
type
label
Monitoring of transcriptional ...... protein production conditions
@ast
Monitoring of transcriptional ...... protein production conditions
@en
prefLabel
Monitoring of transcriptional ...... protein production conditions
@ast
Monitoring of transcriptional ...... protein production conditions
@en
P2093
P2860
P50
P356
P1433
P1476
Monitoring of transcriptional ...... protein production conditions
@en
P2093
Anamitra Bhattacharyya
Jari Rautio
Markku Saloheimo
Michael Maurer
P2860
P2888
P356
10.1186/1471-2164-8-179
P407
P577
2007-06-19T00:00:00Z
P5875
P6179
1036293890