A complex mechanism for inducer mediated tau polymerization.
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The effect of a DeltaK280 mutation on the unfolded state of a microtubule-binding repeat in TauNucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constantsHeat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.Three repeat isoforms of tau inhibit assembly of four repeat tau filamentsQuantitative characterization of heparin binding to Tau protein: implication for inducer-mediated Tau filament formation.Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathiesIn vitro aggregation assays using hyperphosphorylated tau protein.The earliest tau dysfunction in Alzheimer's disease? Tau phosphorylated at s422 as a toxic seedPseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.Understanding the kinetic roles of the inducer heparin and of rod-like protofibrils during amyloid fibril formation by Tau proteinSecondary nucleating sequences affect kinetics and thermodynamics of tau aggregation.Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitroInferring Mechanistic Parameters from Amyloid Formation Kinetics by Approximate Bayesian Computation.Hsp70 alters tau function and aggregation in an isoform specific mannerPseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization.Signature of an aggregation-prone conformation of tau.Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures.GSK-3beta phosphorylation of functionally distinct tau isoforms has differential, but mild effects.RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth.Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology.FTDP-17 tau mutations induce distinct effects on aggregation and microtubule interactions.HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation.A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo.Production of recombinant tau oligomers in vitro.The distinct structural preferences of tau protein repeat domains
P2860
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P2860
A complex mechanism for inducer mediated tau polymerization.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A complex mechanism for inducer mediated tau polymerization.
@ast
A complex mechanism for inducer mediated tau polymerization.
@en
A complex mechanism for inducer mediated tau polymerization.
@nl
type
label
A complex mechanism for inducer mediated tau polymerization.
@ast
A complex mechanism for inducer mediated tau polymerization.
@en
A complex mechanism for inducer mediated tau polymerization.
@nl
prefLabel
A complex mechanism for inducer mediated tau polymerization.
@ast
A complex mechanism for inducer mediated tau polymerization.
@en
A complex mechanism for inducer mediated tau polymerization.
@nl
P2093
P356
P1433
P1476
A complex mechanism for inducer mediated tau polymerization.
@en
P2093
Carolyn A Rankin
Kellen Voss
Mike Branden
Shaun W Carlson
T Chris Gamblin
P304
P356
10.1021/BI700403A
P407
P577
2007-07-04T00:00:00Z