Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. - Wikidata - wikimedia - TriplyDB

Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.

Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.

http://www.wikidata.org/entity/Q33302126

about

A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes Activity-Based Proteomic Profiling of Deubiquitinating Enzymes in Salmonella-Infected Macrophages Leads to Identification of Putative Function of UCH-L5 in Inflammasome Regulation Panel 4: Recent advances in otitis media in molecular biology, biochemistry, genetics, and animal models.Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2 Deubiquitinating enzymes as promising drug targets for infectious diseases.PKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA1.CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production Divergent functions of Toll-like receptors during bacterial lung infections.CYLD negatively regulates nontypeable Haemophilus influenzae-induced IL-8 expression via phosphatase MKP-1-dependent inhibition of ERK.CYLD-mediated signaling and diseases.Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling Antiinflammatory role of MUC1 mucin during infection with nontypeable Haemophilus influenzae.Nontypeable Haemophilus influenzae-Induced MyD88 Short Expression Is Regulated by Positive IKKβ and CREB Pathways and Negative ERK1/2 Pathway.Critical role of type 1 plasminogen activator inhibitor (PAI-1) in early host defense against nontypeable Haemophilus influenzae (NTHi) infection.Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway.A proteomic characterization of NTHi lysates Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88.Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling Resolvin D1 Dampens Pulmonary Inflammation and Promotes Clearance of Nontypeable Haemophilus influenzae Haemophilus influenzae lysate induces aspects of the chronic obstructive pulmonary disease phenotype Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD.NTHi induction of Cxcl2 and middle ear mucosal metaplasia in mice.Deubiquitylation and regulation of the immune response.Resveratrol suppresses NTHi-induced inflammation via up-regulation of the negative regulator MyD88 short.Differential regulation of Streptococcus pneumoniae-induced human MUC5AC mucin expression through distinct MAPK pathways.An in vitro model of murine middle ear epithelium.CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes.The Deubiquitinating Enzyme Cylindromatosis Dampens CD8+ T Cell Responses and Is a Critical Factor for Experimental Cerebral Malaria and Blood-Brain Barrier Damage Synergistic and feedback signaling mechanisms in the regulation of inflammation in respiratory infections.PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications.What have we learned from murine models of otitis media?Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease.The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi).Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD.PAI-1 inhibits development of chronic otitis media and tympanosclerosis in a mouse model of otitis media

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Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice.

http://www.wikidata.org/entity/Q33302126

description

2007 nî lūn-bûn

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2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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Tumor suppressor CYLD acts as ...... e middle ear and lung of mice.

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Tumor suppressor CYLD acts as ...... e middle ear and lung of mice.

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Chang-Hoon Woo

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Haidong Xu

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Hajime Ishinaga

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Haodong Xu

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Hirofumi Jono

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Jae Hyang Lim

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Jian-Dong Li

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Patricia Bourne

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Tomoaki Koga

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Toll-like receptor signalling

Glucocorticoids synergize with IL-1beta to induce TLR2 expression via MAP Kinase Phosphatase-1-dependent dual Inhibition of MAPK JNK and p38 in epithelial cells

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

Identification of the familial cylindromatosis tumour-suppressor gene

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

Themes and variations on ubiquitylation

Regulatory functions of ubiquitination in the immune system

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