High-affinity naloxone binding to filamin a prevents mu opioid receptor-Gs coupling underlying opioid tolerance and dependence.
about
Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylationMaternally administered sustained-release naltrexone in rats affects offspring neurochemistry and behaviour in adulthoodDistinct regional and subcellular localization of the actin-binding protein filamin A in the mature rat brainNaloxone's pentapeptide binding site on filamin A blocks Mu opioid receptor-Gs coupling and CREB activation of acute morphineOxycodone plus ultra-low-dose naltrexone attenuates neuropathic pain and associated mu-opioid receptor-Gs coupling.Human abuse liability assessment of oxycodone combined with ultra-low-dose naltrexone.Glial TLR4 signaling does not contribute to opioid-induced depression of respiration.Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy.Nanoscale effects of ethanol and naltrexone on protein organization in the plasma membrane studied by photoactivated localization microscopy (PALM).Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.Naltrexone treatment reverses astrocyte atrophy and immune dysfunction in self-harming macaques.Ultralow Dose of Naloxone as an Adjuvant to Intrathecal Morphine Infusion Improves Perceived Quality of Sleep but Fails to Alter Persistent Pain: A Randomized, Double-blind, Controlled Study.Why is neuroimmunopharmacology crucial for the future of addiction research?Opioid antagonists for pain.Oxycodone combined with opioid receptor antagonists: efficacy and safety.Challenges for opioid receptor nomenclature: IUPHAR Review 9.The narcotic bowel syndrome: a recent update.Glial dysfunction and persistent neuropathic postsurgical pain.Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats.Ultra-Low Doses of Naltrexone Enhance the Antiallodynic Effect of Pregabalin or Gabapentin in Neuropathic Rats.Potentiation of buprenorphine antinociception with ultra-low dose naltrexone in healthy subjects.
P2860
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P2860
High-affinity naloxone binding to filamin a prevents mu opioid receptor-Gs coupling underlying opioid tolerance and dependence.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
High-affinity naloxone binding ...... ioid tolerance and dependence.
@ast
High-affinity naloxone binding ...... ioid tolerance and dependence.
@en
High-affinity naloxone binding ...... ioid tolerance and dependence.
@nl
type
label
High-affinity naloxone binding ...... ioid tolerance and dependence.
@ast
High-affinity naloxone binding ...... ioid tolerance and dependence.
@en
High-affinity naloxone binding ...... ioid tolerance and dependence.
@nl
prefLabel
High-affinity naloxone binding ...... ioid tolerance and dependence.
@ast
High-affinity naloxone binding ...... ioid tolerance and dependence.
@en
High-affinity naloxone binding ...... ioid tolerance and dependence.
@nl
P2860
P1433
P1476
High-affinity naloxone binding ...... ioid tolerance and dependence.
@en
P2093
Hoau-Yan Wang
Lindsay H Burns
P2860
P356
10.1371/JOURNAL.PONE.0001554
P407
P577
2008-02-06T00:00:00Z