Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
about
A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individualsSemisynthetic combinatorial antibody libraries: a chemical solution to the diversity problemAssembly of combinatorial antibody libraries on phage surfaces: the gene III siteRecombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitroThe use of mRNA display to select high-affinity protein-binding peptidesDelivery of drugs bound to erythrocytes: new avenues for an old intravascular carrierSelection of apoptotic cell specific human antibodies from adult bone marrowOn the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune responseErythropoiesis: Splenic Immunoglobulin Variable Region Genes Encoding Red Blood Cell Binding Fab Fragments in Autoimmune Hemolytic Anemia.Ebola virus can be effectively neutralized by antibody produced in natural human infection.A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.Molecular analysis of HIV-1 gp120 antibody response using isotype IgM and IgG phage display libraries from a long-term non-progressor HIV-1-infected individual.A neutralizing recombinant human antibody Fab fragment against Puumala hantavirus.Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.Human combinatorial antibody libraries to hepatitis B surface antigen.A binary plasmid system for shuffling combinatorial antibody libraries.Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display.Neutralizing human Fab fragments against measles virus recovered by phage displayMolecular analysis of the human autoantibody response to alpha-fodrin in Sjögren's syndrome reveals novel apoptosis-induced specificity.The role of somatic mutation in determining the affinity of anti-DNA antibodies.In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin libraryIdentification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus.Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses.Construction of human Fab library and isolation of monoclonal Fabs with rabies virus-neutralizing ability.Cloning of a human autoimmune response: preparation and sequencing of a human anti-thyroglobulin autoantibody using a combinatorial approach.Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries.Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.Non-human primate immune libraries combined with germline humanization: an (almost) new, and powerful approach for the isolation of therapeutic antibodies.Mining human antibody repertoires.By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selectionPeptide-displaying phage technology in glycobiologyGeneration and Characterization of an scFv Directed against Site II of Rabies Glycoprotein.Human organ-specific autoimmune disease. Molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic immunodominant region and restricted immunoglobulin gene usage in the target organTransplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognitionPathogenic and Epiphenomenal Anti-DNA Antibodies in SLE.Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potentialProduction and characterization of a human recombinant monoclonal Fab fragment specific for influenza A viruses.The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection.A human recombinant Fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4
P2860
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P2860
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@ast
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@en
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.
@nl
type
label
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@ast
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@en
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.
@nl
prefLabel
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@ast
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@en
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.
@nl
P2093
P2860
P356
P1476
Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
@en
P2093
D R Burton
M A Persson
R H Caothien
P2860
P304
P356
10.1073/PNAS.88.6.2432
P407
P577
1991-03-01T00:00:00Z