The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies.
about
Deep sequencing in library selection projects: what insight does it bring?A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein InterfacesCDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic AntibodiesMolecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor regionSpecific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody FragmentDirected Chemical Evolution with an Outsized Genetic CodeImmunoglobulin heavy chain diversity in Pteropid bats: evidence for a diverse and highly specific antigen binding repertoirePrediction of site-specific interactions in antibody-antigen complexes: the proABC method and serverThermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions.MoFvAb: Modeling the Fv region of antibodies.Systematic analysis of short internal indels and their impact on protein folding.How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoireTwo-state selection of conformation-specific antibodiesThe importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.Identification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display.Stability and CDR composition biases enrich binder functionality landscapes.Monobodies and other synthetic binding proteins for expanding protein scienceA portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.Generation of recombinant guinea pig antibody fragments to the human GABAC receptor.Identification of nitrated immunoglobulin variable regions in the HIV-infected human brain: implications in HIV infection and immune response.A novel β-loop scaffold of phage-displayed peptides for highly specific affinities.Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions.Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expressionApplication of circular consensus sequencing and network analysis to characterize the bovine IgG repertoirePackaging biological cargoes in mesoporous materials: opportunities for drug deliveryLarge scale production of phage antibody libraries using a bioreactor.High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin DomainsStreamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step.Ligand-targeted theranostic nanomedicines against cancerStrong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.Generation and analyses of human synthetic antibody libraries and their application for protein microarrays.Tyrosine residues mediate fibril formation in a dynamic light chain dimer interface.Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle.Antigen-antibody interface properties: composition, residue interactions, and features of 53 non-redundant structures.A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold.Natural and man-made V-gene repertoires for antibody discovery.Stereo-selective binding of monoclonal antibodies to the poly-γ-D-glutamic acid capsular antigen of Bacillus anthracisConservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodiesProtein-protein interaction and quaternary structure.Killer peptide: a novel paradigm of antimicrobial, antiviral and immunomodulatory auto-delivering drugs.
P2860
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P2860
The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The intrinsic contributions of ...... and specificity of antibodies.
@ast
The intrinsic contributions of ...... and specificity of antibodies.
@en
The intrinsic contributions of ...... and specificity of antibodies.
@nl
type
label
The intrinsic contributions of ...... and specificity of antibodies.
@ast
The intrinsic contributions of ...... and specificity of antibodies.
@en
The intrinsic contributions of ...... and specificity of antibodies.
@nl
prefLabel
The intrinsic contributions of ...... and specificity of antibodies.
@ast
The intrinsic contributions of ...... and specificity of antibodies.
@en
The intrinsic contributions of ...... and specificity of antibodies.
@nl
P2093
P1476
The intrinsic contributions of ...... and specificity of antibodies.
@en
P2093
Frederic A Fellouse
Gabriele Schaefer
Lihua Shao
Sachdev S Sidhu
Sara Birtalan
Yingnan Zhang
P304
P356
10.1016/J.JMB.2008.01.093
P407
P577
2008-02-12T00:00:00Z