Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
about
PKCĪµ promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondriaAMPK as a potential anticancer target - friend or foe?Sirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismHigh-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease modelReactive oxygen species (ROS) homeostasis and redox regulation in cellular signalingAcquisition of mitochondrial dysregulation and resistance to mitochondrial-mediated apoptosis after genotoxic insult in normal human fibroblasts: a possible model for early stage carcinogenesisChemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cellsA simple high-content cell cycle assay reveals frequent discrepancies between cell number and ATP and MTS proliferation assaysMultiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheresEffects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinaseThe role of the DNA damage response kinase ataxia telangiectasia mutated in neuroprotectionAMPK: a nutrient and energy sensor that maintains energy homeostasisAssociation analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.Radiation induces senescence and a bystander effect through metabolic alterationsATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROSDifferential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infectionMitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.Common variants near ATM are associated with glycemic response to metformin in type 2 diabetesAberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.Tug of war between survival and death: exploring ATM function in cancer.Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancerNicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation.A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53.Role of AMPK in UVB-induced DNA damage repair and growth control.A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphologyOxidative phosphorylation-dependent regulation of cancer cell apoptosis in response to anticancer agentsATM and LKB1 dependent activation of AMPK sensitizes cancer cells to etoposide-induced apoptosisProteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches.Low-dose etoposide-treatment induces endoreplication and cell death accompanied by cytoskeletal alterations in A549 cells: Does the response involve senescence? The possible role of vimentin.Chloroquine increases phosphorylation of AMPK and Akt in myotubes.Induced pluripotent stem cells from ataxia-telangiectasia recapitulate the cellular phenotype.Maintenance of mitochondrial DNA by the Caenorhabditis elegans ATR checkpoint protein ATL-1.Severe mitochondrial damage associated with low-dose radiation sensitivity in ATM- and NBS1-deficient cells.Mitochondrial reactive oxygen species-mediated genomic instability in low-dose irradiated human cells through nuclear retention of cyclin D1.TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.Mitochondria and reactive oxygen species.Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells.Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
P2860
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P2860
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
description
2008 nĆ® lÅ«n-bĆ»n
@nan
2008 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Ō±ÕŗÖÕ«Õ¬Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2008 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ”ÕŗÖÕ«Õ¬Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2008幓ć®č«ę
@ja
2008幓č«ę
@yue
2008幓č«ę
@zh-hant
2008幓č«ę
@zh-hk
2008幓č«ę
@zh-mo
2008幓č«ę
@zh-tw
2008幓č®ŗę
@wuu
name
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@ast
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@en
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.
@nl
type
label
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@ast
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@en
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.
@nl
prefLabel
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@ast
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@en
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.
@nl
P2093
P2860
P1433
P1476
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
@en
P2093
P2860
P356
10.1371/JOURNAL.PONE.0002009
P407
P50
P577
2008-04-23T00:00:00Z