Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold.
about
Affibody-DyLight conjugates for in vivo assessment of HER2 expression by near-infrared optical imagingSelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and XaperonesMolecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agentsSequestration of the Abeta peptide prevents toxicity and promotes degradation in vivoHigh-affinity target binding engineered via fusion of a single-domain antibody fragment with a ligand-tailored SH3 domainSonoporation delivery of monoclonal antibodies against human papillomavirus 16 E6 restores p53 expression in transformed cervical keratinocytesAn albumin-derived peptide scaffold capable of binding and catalysisSystematic engineering of uniform, highly efficient, targeted and shielded viral-mimetic nanoparticlesRational design for multifunctional non-liposomal lipid-based nanocarriers for cancer management: theory to practice.Engineering bispecificity into a single albumin-binding domain.Recombinant amyloid beta-peptide production by coexpression with an affibody ligand.Generation of tumour-necrosis-factor-alpha-specific affibody molecules capable of blocking receptor binding in vitro.A modular IgG-scFv bispecific antibody topology.Ribosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies.Phage display and molecular imaging: expanding fields of vision in living subjects.In vivo targeting of HER2-positive tumor using 2-helix affibody molecules.A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expressionPeptide aptamers: development and applications.An intein-mediated site-specific click conjugation strategy for improved tumor targeting of nanoparticle systems.The HER2-binding affibody molecule (Z(HER2∶342))₂ increases radiosensitivity in SKBR-3 cells.Effective molarity redux: Proximity as a guiding force in chemistry and biology.An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion proteinImproving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domainImaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 affibody moleculeHER2- and EGFR-specific affiprobes: novel recombinant optical probes for cell imaging.Evaluation of 99mTc-Z IGF1R:4551-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expressionHER2-affitoxin: a potent therapeutic agent for the treatment of HER2-overexpressing tumors.Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of RadioactivityDesign of a PDZbody, a bivalent binder of the E6 protein from human papillomavirusIn vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library.A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold.Role of ErbB Receptors in Cancer Cell Migration and InvasionBeyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis.PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR:2377 affibody molecules.Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.Using in-vivo fluorescence imaging in personalized cancer diagnostics and therapy, an image and treat paradigm.Sample preparation: the forgotten beginning.Engineering hepatitis B virus core particles for targeting HER2 receptors in vitro and in vivo.
P2860
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P2860
Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Alternative binding proteins: ...... l three-helix bundle scaffold.
@ast
Alternative binding proteins: ...... l three-helix bundle scaffold.
@en
Alternative binding proteins: ...... l three-helix bundle scaffold.
@nl
type
label
Alternative binding proteins: ...... l three-helix bundle scaffold.
@ast
Alternative binding proteins: ...... l three-helix bundle scaffold.
@en
Alternative binding proteins: ...... l three-helix bundle scaffold.
@nl
prefLabel
Alternative binding proteins: ...... l three-helix bundle scaffold.
@ast
Alternative binding proteins: ...... l three-helix bundle scaffold.
@en
Alternative binding proteins: ...... l three-helix bundle scaffold.
@nl
P2860
P1433
P1476
Alternative binding proteins: ...... l three-helix bundle scaffold.
@en
P2093
Per-Ake Nygren
P2860
P304
P356
10.1111/J.1742-4658.2008.06438.X
P407
P577
2008-04-24T00:00:00Z