Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.
about
A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity.Integrating mass spectrometry of intact protein complexes into structural proteomicsKinetic study of beta-amyloid residue accessibility using reductive alkylation and mass spectrometry.Interaction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment.Proteases of Dermatophagoides pteronyssinusStableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions.Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.Protein-peptide affinity determination using an h/d exchange dilution strategy: application to antigen-antibody interactionsComparison of Two ESI MS Based H/D Exchange Methods for Extracting Protein Folding Energies.Target deconvolution techniques in modern phenotypic profiling.Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.Global analysis of protein folding thermodynamics for disease state characterizationSlow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry.Identification of protein binding partners of small molecules using label-free methods.Theory of the Protein Equilibrium Population Snapshot by H/D Exchange Electrospray Ionization Mass Spectrometry (PEPS-HDX-ESI-MS) Method used to obtain Protein Folding Energies/Rates and Selected Supporting Experimental Evidence.Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidationFalse-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform.Protein stability by number: high-throughput and statistical approaches to one of protein science's most difficult problems.Identification of ligand-target pairs from combined libraries of small molecules and unpurified protein targets in cell lysates.Painting proteins with covalent labels: what's in the picture?Affinity purification in target identification: the specificity challenge.Quantitation of protein-protein interactions by thermal stability shift analysisThermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes.Advances in identification and validation of protein targets of natural products without chemical modification.Emerging Methods in Chemoproteomics with Relevance to Drug Discovery.Protein-protein binding affinities by pulse proteolysis: application to TEM-1/BLIP protein complexes.Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries.Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome.Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.Apparent activation energies of protein-protein complex dissociation in the gas-phase determined by electrospray mass spectrometry.Mass spectrometry methods to study protein-metabolite interactions.Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements.Thermodynamic Analysis of the Geldanamycin-Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach.Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry.Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique.Protein Stability: Enhancement and Measurement.The Role of Mass Spectrometry in Structural Studies of Flavin-Based Electron Bifurcating EnzymesLabel-free technologies for target identification and validation
P2860
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P2860
Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@ast
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@en
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@nl
type
label
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@ast
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@en
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@nl
prefLabel
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@ast
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@en
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@nl
P2093
P356
P1433
P1476
Thermodynamic analysis of prot ...... s spectrometry-based strategy.
@en
P2093
Graham M West
Liangjie Tang
Michael C Fitzgerald
P304
P356
10.1021/AC702610A
P407
P577
2008-05-06T00:00:00Z