Neonatal alloimmune thrombocytopenia due to anti-HPA 1a antibodies; the level of maternal antibodies predicts the severity of thrombocytopenia in the newborn.
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Neonatal thrombocytopenia: causes and managementHuman platelet antigen 1 (HPA 1) genotyping with 5' nuclease assay and sequence-specific primers reveals a single nucleotide deletion in intron 2 of the HPA 1a allele of platelet glycoprotein IIIa.Anti-HPA-1a-mediated platelet phagocytosis by monocytes in vitro and its inhibition by Fc gamma receptor (FcgammaR) reactive reagents.Rapid and reliable genotyping of human platelet antigen (HPA)-1, -2, -3, -4, and -5 a/b and Gov a/b by melting curve analysis.The natural history of maternal immunization against foetal platelet alloantigens.Collaborative study to establish the first international standard for quantitation of anti-HPA-1a.Reactivity of T cells from women with antibodies to the human platelet antigen (HPA)-1a to peptides encompassing the HPA-1 polymorphism.Prospective epidemiologic study of the outcome and cost-effectiveness of antenatal screening to detect neonatal alloimmune thrombocytopenia due to anti-HPA-1a.Predictive value of sequential maternal anti-HPA-1a antibody concentrations for the severity of fetal alloimmune thrombocytopenia.Maternal human platelet antigen-1a antibody level correlates with the platelet count in the newborns: a retrospective study.Advances in the management of alloimmune thrombocytopenia.Cost-effectiveness of antenatal screening for neonatal alloimmune thrombocytopenia.Management and outcome of 200 cases of fetomaternal alloimmune thrombocytopenia.HPA-1a antibody potency and bioactivity do not predict severity of fetomaternal alloimmune thrombocytopenia.The alloimmune response to the human platelet antigen-1a is not related to maternal-fetal killer immunoglobulinlike receptor/HLA-Cw combinations.Severe fetomaternal alloimmune thrombocytopenia due to anti-human platelet antigen (HPA)-1a in a mother with a rare and silenced ITGB3*0101 (GPIIIa) allele.Developing recombinant HPA-1a-specific antibodies with abrogated Fcgamma receptor binding for the treatment of fetomaternal alloimmune thrombocytopenia.Reconsidering fetal and neonatal alloimmune thrombocytopenia with a focus on screening and prevention.Detection of human platelet antigen-1a alloantibodies in cases of fetomaternal alloimmune thrombocytopenia using recombinant β3 integrin fragments coupled to fluorescently labeled beads.A review of pathophysiology and current treatment for neonatal alloimmune thrombocytopenia (NAIT) and introducing the Australian NAIT registry.The development of severe neonatal alloimmune thrombocytopenia due to anti-HPA-1a antibodies is correlated to maternal ABO genotypes.Neonatal alloimmune thrombocytopenia: pathogenesis, diagnosis and management.Current perspectives on fetal and neonatal alloimmune thrombocytopenia - increasing clinical concerns and new treatment opportunities.Frequency distribution of human platelet antigens in the Indian population.Interlaboratory workshop on anti-HPA-1a alloantibody quantification with the mAb-specific immobilization of platelet antigen technique.A variable number of tandem repeats polymorphism influences the transcriptional activity of the neonatal Fc receptor alpha-chain promoter.
P2860
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P2860
Neonatal alloimmune thrombocytopenia due to anti-HPA 1a antibodies; the level of maternal antibodies predicts the severity of thrombocytopenia in the newborn.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@ast
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@en
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@nl
type
label
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@ast
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@en
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@nl
prefLabel
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@ast
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@en
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@nl
P2093
P1476
Neonatal alloimmune thrombocyt ...... rombocytopenia in the newborn.
@en
P2093
P304
P356
10.1111/J.1471-0528.2000.TB13315.X
P577
2000-05-01T00:00:00Z