A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.
about
Animal models of colorectal cancerInducible in vivo genome editing with CRISPR-Cas9CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 statusAcute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activationApc and p53 interaction in DNA damage and genomic instability in hepatocytes.Molecular basis for the tissue specificity of β-catenin oncogenesis.Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior.Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesisComprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling.CKIα ablation highlights a critical role for p53 in invasiveness control.Targeting Zfp148 activates p53 and reduces tumor initiation in the gut.Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine.PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
P2860
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P2860
A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A limited role for p53 in modu ...... of Apc loss in the intestine.
@ast
A limited role for p53 in modu ...... of Apc loss in the intestine.
@en
type
label
A limited role for p53 in modu ...... of Apc loss in the intestine.
@ast
A limited role for p53 in modu ...... of Apc loss in the intestine.
@en
prefLabel
A limited role for p53 in modu ...... of Apc loss in the intestine.
@ast
A limited role for p53 in modu ...... of Apc loss in the intestine.
@en
P2093
P2860
P50
P356
P1433
P1476
A limited role for p53 in modu ...... of Apc loss in the intestine.
@en
P2093
Alicia Cole
Valerie S Meniel
Victoria Marsh
P2860
P2888
P356
10.1186/1471-2407-8-162
P407
P577
2008-06-05T00:00:00Z
P5875
P6179
1017228022