A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma
about
Adoptive immunotherapy for cancer: building on successAdoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanomaEradication of melanomas by targeted elimination of a minor subset of tumor cellsCancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesT-cell clonotypes in cancerAdoptive T cell therapy: Addressing challenges in cancer immunotherapyCellular Immune Responses and Immune Escape Mechanisms in Breast Cancer: Determinants of ImmunotherapyCell-based Immunotherapy for Colorectal Cancer with Cytokine-induced Killer CellsSorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?Advances in the treatment of metastatic melanoma: adoptive T-cell therapyStructure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicityT-cell receptor gene therapy--ready to go viral?Adoptive transfer of vaccine-induced peripheral blood mononuclear cells to patients with metastatic melanoma following lymphodepletion.In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomesChimeric receptor mRNA transfection as a tool to generate antineoplastic lymphocytesAcquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cellsCSPG4: a prototype oncoantigen for translational immunotherapy studies.Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanomaRapid accumulation of adoptively transferred CD8+ T cells at the tumor site is associated with long-term control of SV40 T antigen-induced tumors.Adoptive transfer of unselected or leukemia-reactive T-cells in the treatment of relapse following allogeneic hematopoietic cell transplantation.T cells take aim at cancerHow Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway.Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies.Large-scale depletion of CD25+ regulatory T cells from patient leukapheresis samplesTransfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions.Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.CD8+ T-cell memory in tumor immunology and immunotherapy.Combined IL-21 and low-dose IL-2 therapy induces anti-tumor immunity and long-term curative effects in a murine melanoma tumor model.Transduction of an HLA-DP4-restricted NY-ESO-1-specific TCR into primary human CD4+ lymphocytes.Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapyProgramming CD8+ T cells for effective immunotherapy.Persistence of EBV antigen-specific CD8 T cell clonotypes during homeostatic immune reconstitution in cancer patients.The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapyPersistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans.Adoptive T cell immunotherapy for cancer.Efficacy and safety of HLA-B7/beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) in patients with metastatic melanoma.Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapyFludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism.
P2860
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P2860
A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@ast
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@en
type
label
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@ast
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@en
prefLabel
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@ast
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@en
P2093
P2860
P1476
A phase I study of nonmyeloabl ...... ients with metastatic melanoma
@en
P2093
Azam Nahvi
Claudia A Seipp
Donald E White
Douglas J Schwartzentruber
Francesco M Marincola
James C Yang
John R Wunderlich
Kathleen E Morton
Linda Rogers-Freezer
Mark E Dudley
P2860
P304
P356
10.1097/00002371-200205000-00007
P577
2002-05-01T00:00:00Z